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Clinical Implications of Moderate Coronary Stenosis on Coronary Computed Tomography Angiography in Patients with Stable Angina.

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dc.contributor.author장양수-
dc.contributor.author김충기-
dc.contributor.author홍성진-
dc.contributor.author안철민-
dc.contributor.author김중선-
dc.contributor.author김병극-
dc.contributor.author고영국-
dc.contributor.author최병욱-
dc.contributor.author최동훈-
dc.contributor.author홍명기-
dc.date.accessioned2018-10-05T07:02:56Z-
dc.date.available2018-10-05T07:02:56Z-
dc.date.issued2018-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/163362-
dc.description.abstractPURPOSE: The present study investigated the diagnostic accuracy and clinical implications of moderate stenosis (50-69%, Coronary Artery Disease Reporting and Data System, grade 3) on coronary computed tomography angiography (CCTA), compared with invasive coronary angiography (ICA). MATERIALS AND METHODS: Two hundred and seventy-six patients who underwent ICA due to moderate stenosis alone on CCTA were selected from our prospective registry cohort. RESULTS: Diagnostic concordance between CCTA and ICA was found in only 50 (18%) patients. Among the 396 vessels and 508 segments with moderate stenosis, diagnostic concordance was found in 132 vessels (33%) and 127 segments (25%). Segments with calcified plaque had lower diagnostic concordance than those with mixed or non-calcified plaque (22% vs. 28% vs. 27%, respectively, p=0.001). While calcified plaque burden did not have an influence on severe stenosis (≥70%) on ICA, higher burden of non-calcified plaque was correlated with a greater incidence of ICA-based severe stenosis, which was more frequent in patients with ≥3 segments of non-calcified plaque (75%) than those without non-calcified plaque (22%, p<0.001). Typical angina and mixed or non-calcified plaque were correlated with a higher incidence of under-diagnosis, while the use of next-generation computed tomography scanners reduced the incidence of under-diagnosis. Increased body weight, left circumflex artery involvement, and calcified plaque were independent factors that increased the risk of over-diagnosis of CCTA. CONCLUSION: The diagnosis of moderate stenosis by CCTA may be limited in estimating the exact degree of ICA-based anatomical stenosis. Unlike calcific burden, non-calcific burden was positively correlated with the presence of severe stenosis on ICA.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherYonsei University-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleClinical Implications of Moderate Coronary Stenosis on Coronary Computed Tomography Angiography in Patients with Stable Angina.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorChoongki Kim-
dc.contributor.googleauthorSung-Jin Hong-
dc.contributor.googleauthorChul-Min Ahn-
dc.contributor.googleauthorJung-Sun Kim-
dc.contributor.googleauthorByeong-Keuk Kim-
dc.contributor.googleauthorYoung-Guk Ko-
dc.contributor.googleauthorByoung-Wook Choi-
dc.contributor.googleauthorDonghoon Choi-
dc.contributor.googleauthorYangsoo Jang-
dc.contributor.googleauthorMyeong-Ki Hong-
dc.identifier.doi10.3349/ymj.2018.59.8.937-
dc.contributor.localIdA03448-
dc.contributor.localIdA01061-
dc.contributor.localIdA04403-
dc.contributor.localIdA02269-
dc.contributor.localIdA00961-
dc.contributor.localIdA00493-
dc.contributor.localIdA00127-
dc.contributor.localIdA04059-
dc.contributor.localIdA04053-
dc.contributor.localIdA04391-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid30187700-
dc.subject.keywordCoronary artery disease-
dc.subject.keywordcomputed tomography angiography-
dc.subject.keywordcoronary stenosis-
dc.contributor.alternativeNameJang, Yang Soo-
dc.contributor.alternativeNameKim, Choong Ki-
dc.contributor.alternativeNameHong, Sung Jin-
dc.contributor.alternativeNameAhn, Chul Min-
dc.contributor.alternativeNameKim, Jung Sun-
dc.contributor.alternativeNameKim, Byeong Keuk-
dc.contributor.alternativeNameKo, Young Guk-
dc.contributor.alternativeNameChoi, Byoung Wook-
dc.contributor.alternativeNameChoi, Dong Hoon-
dc.contributor.alternativeNameHong, Myeong Ki-
dc.contributor.affiliatedAuthorJang, Yang Soo-
dc.contributor.affiliatedAuthorKim, Choong Ki-
dc.contributor.affiliatedAuthorHong, Sung Jin-
dc.contributor.affiliatedAuthorAhn, Chul Min-
dc.contributor.affiliatedAuthorKim, Jung Sun-
dc.contributor.affiliatedAuthorKim, Byeong Keuk-
dc.contributor.affiliatedAuthorKo, Young Guk-
dc.contributor.affiliatedAuthorChoi, Byoung Wook-
dc.contributor.affiliatedAuthorChoi, Dong Hoon-
dc.contributor.affiliatedAuthorHong, Myeong Ki-
dc.citation.volume59-
dc.citation.number8-
dc.citation.startPage937-
dc.citation.endPage944-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.59(8) : 937-944, 2018-
dc.identifier.rimsid61027-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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