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Comparison between Wavefront-optimized and corneal Wavefront-guided Transepithelial photorefractive keratectomy in moderate to high astigmatism

 Ikhyun Jun  ;  David Sung Yong Kang  ;  Samuel Arba-Mosquera  ;  Jin Young Choi  ;  Hyung Keun Lee  ;  Eung Kweon Kim  ;  Kyoung Yul Seo  ;  Tae-Im Kim 
 BMC OPHTHALMOLOGY, Vol.18(1) : 154, 2018 
Journal Title
Issue Date
Adolescent ; Adult ; Astigmatism/complications/physiopathology/*surgery ; Corneal Topography ; Corneal Wavefront Aberration/diagnosis/*etiology/surgery ; Corneal/pathology/*surgery Epithelium ; Female ; Follow-Up Studies ; Humans ; Excimer/*therapeutic use Lasers ; Male ; Myopia/complications/physiopathology/*surgery ; Photorefractive Keratectomy/*methods ; Postoperative Period ; Ocular *Refraction ; Retrospective Studies ; Treatment Outcome ; Visual Acuity ; Young Adult
Astigmatism ; Corneal Wavefront-guided ; Transepithelial photorefractive keratectomy ; Wavefront-optimized
BACKGROUND: To compare the clinical outcomes of wavefront-optimized (WFO) transepithelial photorefractive keratectomy (trans-PRK) and corneal wavefront-guided (CWFG) trans-PRK for myopic eyes with moderate to high astigmatism. METHODS: One hundred ninety-six eyes (196 patients) with moderate to high astigmatism (>/= 1.75 D) treated with WFO or CWFG trans-PRK (101 and 95 eyes, respectively) were retrospectively registered. Safety, efficacy, predictability, vector analysis, and corneal aberrations were compared between groups preoperatively and at 6 months postoperatively. RESULTS: At postoperative 6 months, the mean logMAR uncorrected distance visual acuity was similar in the WFO (- 0.07 +/- 0.08) and CWFG (- 0.07 +/- 0.07) groups. Safety, efficacy, and predictability of refractive and visual outcomes were also similar. The correction indices were 1.02 +/- 0.14 and 1.03 +/- 0.13 in the WFO and CWFG groups, respectively, with no significant difference. The absolute values of the angle of error were significantly higher in the WFO group (2.28 +/- 2.44 vs. 1.40 +/- 1.40; P = 0.002). Corneal total root mean square higher-order aberrations and corneal spherical aberrations increased postoperatively in both groups; however, the change was smaller in the CWFG group. Corneal coma showed a significant increase postoperatively only in the WFO group. CONCLUSIONS: WFO and CWFG trans-PRK are safe and effective for correcting moderate to high astigmatism. However, CWFG trans-PRK provides a more predictable astigmatism correction axis and fewer induced corneal aberrations.
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1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Eung Kweon(김응권) ORCID logo https://orcid.org/0000-0002-1453-8042
Kim, Tae Im(김태임) ORCID logo https://orcid.org/0000-0001-6414-3842
Seo, Kyuong Yul(서경률) ORCID logo https://orcid.org/0000-0002-9855-1980
Lee, Hyung Keun(이형근) ORCID logo https://orcid.org/0000-0002-1123-2136
Jun, Ik Hyun(전익현) ORCID logo https://orcid.org/0000-0002-2160-1679
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