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Incidence and prevalence of uveitis in South Korea: a nationwide cohort study

 Tyler Hyungtaek Rim  ;  Sung Soo Kim  ;  Don-Il Ham  ;  Seung-Young Yu  ;  Eun Jee Chung  ;  Sung Chul Lee 
 British Journal of Ophthalmology, Vol.102(1) : 79-83, 2018 
Journal Title
 British Journal of Ophthalmology 
Issue Date
Adult ; Age Distribution ; Follow-Up Studies ; Humans ; Incidence ; Middle Aged ; Population Surveillance/*methods ; Prevalence ; Republic of Korea/epidemiology ; Retrospective Studies ; *Risk Assessment ; Risk Factors ; Sex Distribution ; Time Factors ; Uveitis/*epidemiology
incidence ; prevalence ; south korea ; uveitis: anterior uveitis
AIM: To evaluate the incidence and prevalence of uveitis and associated risk factors in South Korea. METHODS: For this retrospective national cohort study, approximately 1 000 000 Korean residents were randomly selected from the Korean National Health Insurance Service database. Uveitis was defined according to the Korean Classification of Diseases. The uveitis incidence and prevalence were calculated. Sociodemographic factors and comorbidities associated with uveitis were evaluated via Cox proportional regression models. RESULTS: A total of 1 094 440 subjects were evaluated over 7 051 346 person-years (mean follow-up: 6.44 years). Overall, 7447 newly developed uveitis cases were identified during the period of 2007-2013; the average incidence of uveitis was 10.6 per 10 000 person-years (95% CI 10.3 to 10.8). The average incidences of anterior and non-anterior uveitis were 9.0 and 1.5 per 10 000 person-years, respectively. The prevalence rates of uveitis, anterior uveitis and non-anterior uveitis were 17.3, 15.0 and 2.3 per 10 000 persons, respectively, during the period of 2007-2013. Increasing age, male sex, residing in a relatively rural area and high income were associated with uveitis, along with Behcet's disease, juvenile idiopathic arthritis, ankylosing spondylitis, systemic lupus erythematous, ulcerative colitis and tuberculosis. CONCLUSIONS: The overall incidence of uveitis in Korea was similar to those reported in Taiwan and the USA. Despite a potentially inaccurate disease definition, claims data may be useful for monitoring the substantial uveitis burden in South Korea.
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1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Sung Soo(김성수) ORCID logo https://orcid.org/0000-0002-0574-7993
Lee, Sung Chul(이성철) ORCID logo https://orcid.org/0000-0001-9438-2385
Rim, Tyler Hyungtaek(임형택)
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