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Association of platelet count with sarcopenic obesity in postmenopausal women: A nationwide population-based study.

 Woo-Jin Park  ;  Dong-Hyuk Jung  ;  Ji-Won Lee  ;  Jae-Yong Shim  ;  Yu-Jin Kwon 
 Clinica Chimica Acta, Vol.477 : 113-118, 2018 
Journal Title
 Clinica Chimica Acta 
Issue Date
Platelet count ; Postmenopausal women ; Sarcopenic obesity
OBJECTIVES: The aim of this study was to examine the relationship between platelet count and sarcopenic obesity in postmenopausal women. METHOD: This cross-sectional study was conducted using nationally representative data. A total of 2810 postmenopausal women who participated in the 2008-2011 Korea National Health and Nutrition Examination Survey were included in this study. Sarcopenic obesity was defined by a sarcopenia criterion and an obesity criterion. Platelet counts were divided into quartiles as follows: Q, 150-222; Q2, 223-257; Q3, 258-294, and Q4, 295-450 (103/μl). Multiple logistic regression analysis was performed to examine the association between platelet count quartile and sarcopenic obesity after adjusting for confounding factors. RESULTS: The prevalence of sarcopenic obesity in postmenopausal women was 14.8%. Compared to the lowest platelet quartile, the odds ratios and 95% confidence intervals for sarcopenic obesity in the highest quartile were 1.98 (1.36-2.89) in the unadjusted model; 1.93 (1.31-2.83) after adjusting for age; and 1.65 (1.23-2.65) after adjusting for age, systolic blood pressure, homeostatic model assessment insulin resistance (HOMA-IR), triglyceride, total cholesterol, total calorie intake, regular exercise, current smoking status, and education level. CONCLUSIONS: Elevated platelet count (i.e. towards the upper end of the normal range) was significantly associated with sarcopenic obesity in postmenopausal women.
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1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실) > 1. Journal Papers
Yonsei Authors
권유진(Kwon, Yu-Jin) ORCID logo https://orcid.org/0000-0002-9021-3856
박우진(Park, Woo-Jin)
심재용(Shim, Jae Yong) ORCID logo https://orcid.org/0000-0002-9561-9230
이지원(Lee, Ji Won) ORCID logo https://orcid.org/0000-0002-2666-4249
정동혁(Jung, Dong Hyuk) ORCID logo https://orcid.org/0000-0002-3411-0676
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