15 22

Cited 0 times in

Visual rehabilitation in moderate keratoconus: combined corneal wavefront-guided transepithelial photorefractive keratectomy and high-fluence accelerated corneal collagen cross-linking after intracorneal ring segment implantation

Authors
 Hun Lee  ;  David Sung Yong Kang  ;  Byoung Jin Ha  ;  Jin Young Choi  ;  Eung Kweon Kim  ;  Kyoung Yul Seo  ;  Tae-im Kim 
Citation
 BMC Ophthalmology, Vol.17(1) : 270, 2017 
Journal Title
 BMC Ophthalmology 
Issue Date
2017
MeSH
Adult ; Collagen/therapeutic use* ; Corneal Stroma/pathology ; Corneal Stroma/surgery ; Corneal Topography ; Cross-Linking Reagents/therapeutic use* ; Female ; Follow-Up Studies ; Humans ; Keratoconus/diagnosis ; Keratoconus/physiopathology ; Keratoconus/therapy* ; Lenses, Intraocular* ; Male ; Photochemotherapy/methods* ; Photorefractive Keratectomy/methods* ; Prosthesis Implantation/methods ; Refraction, Ocular/physiology ; Retrospective Studies ; Visual Acuity* ; Young Adult
Keywords
Combined corneal wavefront-guided transepithelial photorefractive keratectomy and accelerated corneal collagen cross-linking ; Intracorneal ring segment implantation ; Keratoconus
Abstract
BACKGROUND: To investigate the effects of combined corneal wavefront-guided transepithelial photorefractive keratectomy (tPRK) and accelerated corneal collagen cross-linking (CXL) after intracorneal ring segment (ICRS) implantation in patients with moderate keratoconus. METHODS: Medical records of 23 eyes of 23 patients undergoing combined tPRK and CXL after ICRS implantation were retrospectively analyzed. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest refraction spherical equivalent (MRSE), corneal indices based on Scheimpflug tomography, higher-order aberrations (HOAs), and corneal biomechanical properties were evaluated before and after ICRS implantation, and at 1, 3, and 6 months after combined tPRK and CXL. RESULTS: There were significant improvements in final logMAR UDVA and logMAR CDVA, and reductions in sphere, MRSE, and all corneal indices from baseline. Significant improvements in logMAR UDVA and reductions in sphere, MRSE, maximal keratometry, keratometry at the apex, mean keratometry, and keratoconus index were noted after ICRS implantation. After tPRK and CXL, significant improvements in logMAR UDVA and logMAR CDVA, and reductions in cylinder and all corneal indices were observed. There were significant improvements in final root mean square HOAs and coma aberrations from baseline, but no changes from baseline after ICRS implantation. Significant reductions in final radius and deformation amplitude from baseline were noted. CONCLUSIONS: Combined tPRK and accelerated CXL after ICRS implantation in moderate keratoconus appears to be a safe and effective treatment, providing an improvement in visual acuity, corneal indices, and HOAs.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/161699
DOI
10.1186/s12886-017-0666-1
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실)
Yonsei Authors
김응권(Kim, Eung Kweon)
김태임(Kim, Tae Im)
서경률(Seo, Kyuong Yul)
사서에게 알리기
  feedback
Files in This Item:
T201705588.pdf Download
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse