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Human Immunodeficiency Virus (HIV) and Hepatitis Virus Coinfection among HIV-Infected Korean Patients: The Korea HIV/AIDS Cohort Study

 Yong Chan Kim  ;  Jin Young Ahn  ;  June Myung Kim  ;  Youn Jeong Kim  ;  Dae Won Park  ;  Young Kyung Yoon  ;  Joon Young Song  ;  Shin Woo Kim  ;  Jin Soo Lee  ;  Bo Youl Choi  ;  Yun Su Choi  ;  Ju-yeon Choi  ;  Myung Guk Han  ;  Chun Kang  ;  Jun Yong Choi 
 INFECTION AND CHEMOTHERAPY, Vol.49(4) : 268-274, 2017 
Journal Title
Issue Date
Coinfection ; HIV infection ; Hepatitis B virus ; Hepatitis C virus
BACKGROUND: Despite declines in mortality and morbidity rates of patients with human immunodeficiency virus (HIV) infection as the result of highly active antiretroviral therapy, liver diseases due to chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are a leading cause of death among HIV-infected patients. However, HIV and HBV or HCV coinfection is still poorly documented, and more information is needed to better understand the characteristics of HIV-infected patients in Korea.

MATERIALS AND METHODS: A cross-sectional study was performed to investigate clinical characteristics and prevalence of HBV and HCV infection in HIV patients enrolled in the Korea HIV/acquired immune deficiency syndrome (AIDS) cohort study from 17 institutions between December 2006 and July 2013.

RESULTS: Among the 1,218 HIV-infected participants, 541 were included in this study. The prevalence of HBV-HIV and HCV-HIV coinfection was 5.0% (27/541) and 1.7% (9/541), respectively. There was no patient who was positive for both HBs antigen and HCV antibody. In multivariate logistic regression analysis, HBV unvaccinated status was a significant risk factor for HBV-HIV coinfection (odds ratio = 4.95, 95% confidence interval = 1.43-17.13).

CONCLUSIONS: HBV and HCV infection was more common in HIV-infected persons enrolled in the Korean HIV/AIDS cohort, than in the general population in Korea.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Yong Chan(김용찬)
Kim, June Myung(김준명)
Ahn, Jin Young(안진영) ORCID logo https://orcid.org/0000-0002-3740-2826
Choi, Jun Yong(최준용) ORCID logo https://orcid.org/0000-0002-2775-3315
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