Cited 11 times in
Factors predictive of occult nipple-areolar complex involvement in patients with carcinoma in situ of the breast
DC Field | Value | Language |
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dc.contributor.author | 구자승 | - |
dc.contributor.author | 김민정 | - |
dc.contributor.author | 김승일 | - |
dc.contributor.author | 김은경 | - |
dc.contributor.author | 박병우 | - |
dc.contributor.author | 박세호 | - |
dc.contributor.author | 박형석 | - |
dc.contributor.author | 윤정현 | - |
dc.contributor.author | 조영업 | - |
dc.contributor.author | 황혜성 | - |
dc.date.accessioned | 2018-07-20T12:01:37Z | - |
dc.date.available | 2018-07-20T12:01:37Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 0022-4790 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/161661 | - |
dc.description.abstract | OBJECTIVES: To investigate predictors of occult nipple-areolar complex (NAC) involvement in patients with carcinoma in situ (CIS) and to validate an online probability calculator (CancerMath; www.lifemath.net/cancer/breastcancer/nipplecalc/index.php). METHODS: Mastectomized patients with CIS (n = 104) were retrospectively selected. Clinicopathology and preoperative mammography, ultrasound, and magnetic resonance imaging (MRI) findings were analyzed. RESULTS: Histopathological NAC-positivity was confirmed in 20 (19.2%) patients. Short nipple-tumor distance and suspicious extension to the nipple by mammography were significant but ultrasound was not significant to predict NAC involvement. NAC-positive cases had MRI findings of shorter nipple-tumor distance in both the early and delayed phases. Multivariable regression model showed age >50 years and shorter tumor-nipple distance on the delay phase of MRI were statistically significant predictors of NAC involvement. Area under the receiver operating characteristics curve (AUC) was 0.618 when calculated by CancerMath; however, an AUC of 0.954 was achieved when distance and age were applied together as predictor. CONCLUSIONS: Mammographic and MRI findings were significant for predicting NAC involvement, with distance of the tumor from the nipple in delay phase MRI the most significant predictor of NAC involvement. Therefore, breast MRI could be beneficial for planning nipple-sparing mastectomy in patients with CIS. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Wiley-Liss | - |
dc.relation.isPartOf | JOURNAL OF SURGICAL ONCOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Breast Carcinoma In Situ/diagnostic imaging | - |
dc.subject.MESH | Breast Carcinoma In Situ/pathology* | - |
dc.subject.MESH | Breast Carcinoma In Situ/surgery | - |
dc.subject.MESH | Breast Neoplasms/diagnostic imaging* | - |
dc.subject.MESH | Breast Neoplasms/pathology* | - |
dc.subject.MESH | Breast Neoplasms/surgery | - |
dc.subject.MESH | Carcinoma, Intraductal, Noninfiltrating/pathology | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Logistic Models | - |
dc.subject.MESH | Magnetic Resonance Imaging | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Nipples/pathology* | - |
dc.subject.MESH | Nipples/surgery | - |
dc.subject.MESH | Retrospective Studies | - |
dc.title | Factors predictive of occult nipple-areolar complex involvement in patients with carcinoma in situ of the breast | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Pathology | - |
dc.contributor.googleauthor | Hyeoseong Hwang | - |
dc.contributor.googleauthor | Seho Park | - |
dc.contributor.googleauthor | Ja Seung Koo | - |
dc.contributor.googleauthor | Hyung Seok Park | - |
dc.contributor.googleauthor | Seung Il Kim | - |
dc.contributor.googleauthor | Young Up Cho | - |
dc.contributor.googleauthor | Byeong‐Woo Park | - |
dc.contributor.googleauthor | Jung Hyun Yoon | - |
dc.contributor.googleauthor | Min Jung Kim | - |
dc.contributor.googleauthor | Eun‐Kyung Kim | - |
dc.identifier.doi | 10.1002/jso.24768 | - |
dc.contributor.localId | A00198 | - |
dc.contributor.localId | A00473 | - |
dc.contributor.localId | A00658 | - |
dc.contributor.localId | A00801 | - |
dc.contributor.localId | A01475 | - |
dc.contributor.localId | A01524 | - |
dc.contributor.localId | A01753 | - |
dc.contributor.localId | A02595 | - |
dc.contributor.localId | A05420 | - |
dc.contributor.localId | A05447 | - |
dc.relation.journalcode | J01762 | - |
dc.identifier.eissn | 1096-9098 | - |
dc.identifier.pmid | 28743180 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/abs/10.1002/jso.24768 | - |
dc.subject.keyword | breast neoplasms | - |
dc.subject.keyword | carcinoma in situ | - |
dc.subject.keyword | magnetic resonance imaging | - |
dc.subject.keyword | nipples | - |
dc.subject.keyword | risk factors | - |
dc.contributor.alternativeName | Koo, Ja Seung | - |
dc.contributor.alternativeName | Kim, Min Jung | - |
dc.contributor.alternativeName | Kim, Seung Il | - |
dc.contributor.alternativeName | Kim, Eun Kyung | - |
dc.contributor.alternativeName | Park, Byeong Woo | - |
dc.contributor.alternativeName | Park, Se Ho | - |
dc.contributor.alternativeName | Park, Hyung Seok | - |
dc.contributor.alternativeName | Yoon, Jung Hyun | - |
dc.contributor.alternativeName | Cho, Young Up | - |
dc.contributor.alternativeName | Hwang, Hyeoseong | - |
dc.contributor.affiliatedAuthor | Koo, Ja Seung | - |
dc.contributor.affiliatedAuthor | Kim, Min Jung | - |
dc.contributor.affiliatedAuthor | Kim, Seung Il | - |
dc.contributor.affiliatedAuthor | Kim, Eun-Kyung | - |
dc.contributor.affiliatedAuthor | Park, Byeong Woo | - |
dc.contributor.affiliatedAuthor | Park, Se Ho | - |
dc.contributor.affiliatedAuthor | Park, Hyung Seok | - |
dc.contributor.affiliatedAuthor | Yoon, Jung Hyun | - |
dc.contributor.affiliatedAuthor | Cho, Young Up | - |
dc.contributor.affiliatedAuthor | Hwang, Hyeoseong | - |
dc.contributor.affiliatedAuthor | 구자승 | - |
dc.citation.volume | 116 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 1046 | - |
dc.citation.endPage | 1055 | - |
dc.identifier.bibliographicCitation | JOURNAL OF SURGICAL ONCOLOGY, Vol.116(8) : 1046-1055, 2017 | - |
dc.identifier.rimsid | 61684 | - |
dc.type.rims | ART | - |
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