The purpose of this study was to identify the relationship among dementia knowledge, attitude and care burden of nurses in center for dementia. A total of 101 nurses in center for dementia filled out the structure questionnaires. The data were analyzed using the t-test, ANOVA, and Pearson correlation coefficients. The mean score of dementia knowledge was $18.14{\pm}1.09$ out of 20, and the mean of dementia attitude, care burden were $153.07{\pm}.76$ out of $266, 8.01{\pm}7.09$ out of 64 respectively. There was a significant correlation between care burden and dementia attitude(r=.25, p<.05) and dementia knowledge(r=-.32, p<.001). The results suggest that it is necessary to provide continuos education and support to improve dementia knowledge and change dementia attitude positively of nurses in order to reduce care burden of nurses in center for dementia.