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Usefulness of serial measurement of the red blood cell distribution width to predict 28-day mortality in patients with trauma

DC FieldValueLanguage
dc.contributor.author공태영-
dc.contributor.author박유석-
dc.contributor.author박인철-
dc.contributor.author박종은-
dc.contributor.author유제성-
dc.contributor.author이혜선-
dc.contributor.author정성필-
dc.contributor.author정현수-
dc.date.accessioned2018-07-20T11:53:12Z-
dc.date.available2018-07-20T11:53:12Z-
dc.date.issued2017-
dc.identifier.issn0735-6757-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/161449-
dc.description.abstractBACKGROUND: This is the first study to evaluate the association between the serially measured RDW values and clinical severity in patients surviving >24 h after sustaining trauma. We evaluated the serial measurement and cut-off values of RDW to determine its significance as a prognostic marker of early mortality in patients with suspected severe trauma. METHODS: This study retrospectively analyzed prospective data of eligible adult patients who were admitted to the ED with suspected severe trauma. The RDW was determined on each day of hospitalization. The primary outcome was all-cause mortality within 28-days of ED admission. RESULTS: We included 305 patients who met our inclusion criteria. The multivariate Cox regression model demonstrated that higher RDW values on day 1 (hazard ratio [HR], 1.558; 95% confidence interval [CI], 1.09-2.227; p=0.015) and day 2 (HR, 1.549; 95% CI, 1.046-2.294; p=0.029) were strong independent predictors of short-term mortality among patients with suspected severe trauma. Considering the clinical course of severe trauma patients, the RDW is an important ancillary test for determining severity. Specifically, we found that RDW values >14.4% on day 1 (HR, 4.227; 95% CI: 1.672-10.942; p<0.001) and >14.7% on day 2 (HR, 6.041; 95% CI: 2.361-15.458; p<0.001) increased the hazard 28-day all-cause mortality. CONCLUSION: An increased RDW value is an independent predictor of 28-day mortality in patients with suspected severe trauma. The RDW, routinely obtained as part of the complete blood count without added cost or time, can be serially measured as indicator of severity after trauma.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherW B Saunders-
dc.relation.isPartOfAmerican Journal of Emergency Medicine-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHCritical Pathways-
dc.subject.MESHErythrocyte Indices-
dc.subject.MESHFemale-
dc.subject.MESHHospital Mortality/trends-
dc.subject.MESHHospitalization/statistics & numerical data*-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPredictive Value of Tests-
dc.subject.MESHPrognosis-
dc.subject.MESHProportional Hazards Models-
dc.subject.MESHProspective Studies-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESHShock, Hemorrhagic/blood*-
dc.subject.MESHShock, Hemorrhagic/etiology-
dc.subject.MESHShock, Hemorrhagic/mortality-
dc.subject.MESHTime Factors-
dc.subject.MESHWounds and Injuries/blood*-
dc.subject.MESHWounds and Injuries/complications-
dc.subject.MESHWounds and Injuries/mortality-
dc.titleUsefulness of serial measurement of the red blood cell distribution width to predict 28-day mortality in patients with trauma-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Emergency Medicine-
dc.contributor.googleauthorTaeyoung Kong-
dc.contributor.googleauthorJong Eun Park-
dc.contributor.googleauthorYoo Seok Park-
dc.contributor.googleauthorHye Sun Lee-
dc.contributor.googleauthorJe Sung You-
dc.contributor.googleauthorHyun Soo Chung-
dc.contributor.googleauthorIncheol Park-
dc.contributor.googleauthorSung Phil Chung-
dc.identifier.doi10.1016/j.ajem.2017.06.008-
dc.contributor.localIdA00162-
dc.contributor.localIdA01592-
dc.contributor.localIdA01628-
dc.contributor.localIdA05335-
dc.contributor.localIdA02507-
dc.contributor.localIdA03312-
dc.contributor.localIdA03625-
dc.contributor.localIdA03764-
dc.relation.journalcodeJ00079-
dc.identifier.eissn1532-8171-
dc.identifier.pmid28709714-
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S073567571730445X-
dc.subject.keywordAdmission-
dc.subject.keywordEmergency department-
dc.subject.keywordHemorrhagic shock-
dc.subject.keywordMortality-
dc.subject.keywordRed blood cell distribution width-
dc.subject.keywordTrauma-
dc.contributor.alternativeNameKong, Tae Young-
dc.contributor.alternativeNamePark, Yoo Seok-
dc.contributor.alternativeNamePark, In Cheol-
dc.contributor.alternativeNamePark, Jong Eun-
dc.contributor.alternativeNameYou, Je Sung-
dc.contributor.alternativeNameLee, Hye Sun-
dc.contributor.alternativeNameChung, Sung Pil-
dc.contributor.alternativeNameChung, Hyun Soo-
dc.contributor.affiliatedAuthorKong, Tae Young-
dc.contributor.affiliatedAuthorPark, Yoo Seok-
dc.contributor.affiliatedAuthorPark, In Cheol-
dc.contributor.affiliatedAuthorPark, Jong Eun-
dc.contributor.affiliatedAuthorYou, Je Sung-
dc.contributor.affiliatedAuthorLee, Hye Sun-
dc.contributor.affiliatedAuthorChung, Sung Pil-
dc.contributor.affiliatedAuthorChung, Hyun Soo-
dc.citation.volume35-
dc.citation.number12-
dc.citation.startPage1819-
dc.citation.endPage1827-
dc.identifier.bibliographicCitationAmerican Journal of Emergency Medicine, Vol.35(12) : 1819-1827, 2017-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Emergency Medicine (응급의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers

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