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Retinal pigment epithelium wound healing after traumatic choroidal rupture

Authors
 Joo Youn Shin  ;  Byunghoon Chung  ;  Yun Hyup Na  ;  Jonghyun Lee  ;  Hyewon Chung  ;  Suk Ho Byeon 
Citation
 ACTA OPHTHALMOLOGICA, Vol.95(7) : e582-e586, 2017 
Journal Title
ACTA OPHTHALMOLOGICA
ISSN
 1755-375X 
Issue Date
2017
MeSH
Adolescent ; Adult ; Child ; Choroid/injuries* ; Choroidal Neovascularization/etiology ; Choroidal Neovascularization/pathology ; Eye Injuries/complications ; Eye Injuries/pathology* ; Female ; Fluorescein Angiography/methods* ; Follow-Up Studies ; Fundus Oculi ; Humans ; Male ; Middle Aged ; Retinal Pigment Epithelium/injuries ; Retinal Pigment Epithelium/pathology* ; Retrospective Studies ; Rupture ; Time Factors ; Tomography, Optical Coherence/methods* ; Wound Healing* ; Young Adult
Keywords
choroidal rupture ; fundus autofluorescence ; optical coherence tomography ; retinal pigment epithelium ; wound healing
Abstract
PURPOSE: The aim of this study was to investigate wound healing in the retinal pigment epithelium (RPE) after traumatic indirect choroidal rupture using fundus autofluorescence (FAF) and spectral-domain optical coherence tomography (SD-OCT).

METHODS: A total of 14 eyes of 14 patients with traumatic indirect choroidal rupture were included. Baseline and last follow-up FAF images were compared to evaluate the extent of RPE healing after choroidal rupture, and associated morphologic characteristics were examined by SD-OCT.

RESULTS: The size of the RPE lesion was reduced in five eyes. The change occurred in the fovea in four eyes and in the macula in three eyes. The change was noted in both the fovea and the macula in two eyes; in these cases, the changes were more prominent in the fovea than in the macula. Extra-macular lesions and lesions with deep choroidal involvement did not show any reduction in size. Choroidal neovascularization (CNV) developed in seven eyes. There was no extra-macular CNV.

CONCLUSION: Retinal pigment epithelium (RPE) wound healing after traumatic choroidal rupture is affected by location and extent of the lesion.
Full Text
https://onlinelibrary.wiley.com/doi/abs/10.1111/aos.13300
DOI
10.1111/aos.13300
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Byeon, Suk Ho(변석호) ORCID logo https://orcid.org/0000-0001-8101-0830
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/161374
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