Cited 5 times in
Effect of yttrium-90 radioembolization on outcomes in Asian patients with early to advanced stage hepatocellular carcinoma
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김도영 | - |
dc.contributor.author | 원종윤 | - |
dc.contributor.author | 한광협 | - |
dc.date.accessioned | 2018-07-20T08:34:54Z | - |
dc.date.available | 2018-07-20T08:34:54Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 1386-6346 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/161300 | - |
dc.description.abstract | AIM: The aim of this study was to investigate the effect of yttrium-90 radioembolization on the outcome of Asian patients with early to advanced stage hepatocellular carcinoma (HCC). METHODS: Sixty-two patients were screened and 50 patients (80.6%) were eligible. Response was evaluated using the Response Evaluation Criteria in Solid Tumors (RECIST), and overall survival was estimated using the Kaplan-Meier method. RESULTS: The Barcelona Clinic Liver Cancer (BCLC) stage was A in 40% of patients, B in 24%, and C in 36%; 66% of patients had hepatitis B virus infections. According to RECIST criteria, partial responses occurred in 40% of patients, and stable disease was achieved in 46%. Tumor response was significantly associated with BCLC stage (P = 0.003). The median overall time to progression was 5.8 months (range, 0.9-46.1 months). Follow-up treatments after radioembolization were carried out in 31 patients due to remnant HCC (n = 18) or HCC progression (n = 13). The median overall survival was 40.9 months (95% confidence interval, 10.2-71.6 months). Treatment was tolerable except for one lung toxicity and two hepatic toxicities. CONCLUSION: Yttrium-90 radioembolization appears to be well tolerated and effective in Asian patients with BCLC stage A-C HCC. Follow-up treatments after radioembolization can be safely provided. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Blackwell Publishing | - |
dc.relation.isPartOf | HEPATOLOGY RESEARCH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Effect of yttrium-90 radioembolization on outcomes in Asian patients with early to advanced stage hepatocellular carcinoma | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Internal Medicine | - |
dc.contributor.googleauthor | Hyun Young Woo | - |
dc.contributor.googleauthor | Do Young Kim | - |
dc.contributor.googleauthor | Jeong Heo | - |
dc.contributor.googleauthor | Chang Won Kim | - |
dc.contributor.googleauthor | Suk Kim | - |
dc.contributor.googleauthor | Ki Tae Yoon | - |
dc.contributor.googleauthor | Won Lim | - |
dc.contributor.googleauthor | Young Mi Hong | - |
dc.contributor.googleauthor | Jong Yun Won | - |
dc.contributor.googleauthor | Sangheun Lee | - |
dc.contributor.googleauthor | Kwang Hyub Han | - |
dc.contributor.googleauthor | Mong Cho | - |
dc.identifier.doi | 10.1111/hepr.12759 | - |
dc.contributor.localId | A00385 | - |
dc.contributor.localId | A02443 | - |
dc.contributor.localId | A04268 | - |
dc.relation.journalcode | J00987 | - |
dc.identifier.eissn | 1872-034X | - |
dc.identifier.pmid | 27272116 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/abs/10.1111/hepr.12759 | - |
dc.subject.keyword | hepatocellular carcinoma | - |
dc.subject.keyword | radioembolization | - |
dc.subject.keyword | yttrium-90 | - |
dc.contributor.alternativeName | Kim, Do Young | - |
dc.contributor.alternativeName | Won, Jong Yun | - |
dc.contributor.alternativeName | Han, Kwang Hyup | - |
dc.contributor.affiliatedAuthor | Kim, Do Young | - |
dc.contributor.affiliatedAuthor | Won, Jong Yun | - |
dc.contributor.affiliatedAuthor | Han, Kwang Hyup | - |
dc.citation.volume | 47 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 387 | - |
dc.citation.endPage | 397 | - |
dc.identifier.bibliographicCitation | HEPATOLOGY RESEARCH, Vol.47(5) : 387-397, 2017 | - |
dc.identifier.rimsid | 61222 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.