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Parathyroid Hormone (1-34) Might Not Improve Early Bone Healing after Sinus Augmentation in Healthy Rabbits

DC FieldValueLanguage
dc.contributor.author김기덕-
dc.contributor.author김현실-
dc.contributor.author박원서-
dc.contributor.author정의원-
dc.contributor.author허지선-
dc.date.accessioned2018-07-20T08:17:43Z-
dc.date.available2018-07-20T08:17:43Z-
dc.date.issued2017-
dc.identifier.issn2314-6133-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/161056-
dc.description.abstractPurpose. This study evaluated the effect of administering intermittent parathyroid hormone [PTH (1-34), henceforth PTH] on the early-stage bone healing of maxillary sinus augmentation in healthy rabbits. Materials and Methods. Bovine bone mineral was grafted on the sinuses of 20 female New Zealand white rabbits. The animals were randomly divided into two groups, PTH (n = 10) or saline (n = 10), in which either PTH or saline was injected subcutaneously 5 days a week for 2 weeks. Half of the animals in each group were killed at 2 weeks postoperatively and the other half were killed at 4 weeks postoperatively. The dosage of PTH was 10 μg/kg/day. Radiographic and histomorphometric analyses were performed. Result. The new bone area (NBA) did not differ significantly between the PTH and saline groups. The NBA in the PTH group in the total augmented area and in the demarcated window, center, and Schneiderian membrane regions increased significantly from 2 to 4 weeks. The number of osteoclasts decreased significantly from 2 to 4 weeks in both groups, with no difference between the two groups. Conclusion. Intermittent PTH might not stimulate new bone formation in healthy rabbits during the first 4 weeks of healing.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherHindawi Pub. Co.-
dc.relation.isPartOfBioMed Research International-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAnimals-
dc.subject.MESHCattle-
dc.subject.MESHCell Count-
dc.subject.MESHFemale-
dc.subject.MESHMaxillary Sinus/diagnostic imaging-
dc.subject.MESHMaxillary Sinus/pathology-
dc.subject.MESHMaxillary Sinus/surgery-
dc.subject.MESHNasal Mucosa/surgery-
dc.subject.MESHOrgan Size-
dc.subject.MESHOsteoclasts/pathology-
dc.subject.MESHParathyroid Hormone/pharmacology*-
dc.subject.MESHRabbits-
dc.subject.MESHSinus Floor Augmentation/methods*-
dc.subject.MESHWound Healing/drug effects*-
dc.subject.MESHX-Ray Microtomography-
dc.titleParathyroid Hormone (1-34) Might Not Improve Early Bone Healing after Sinus Augmentation in Healthy Rabbits-
dc.typeArticle-
dc.contributor.collegeCollege of Dentistry-
dc.contributor.departmentDept. of Advanced General Dentistry-
dc.contributor.googleauthorJisun Huh-
dc.contributor.googleauthorUi-Won Jung-
dc.contributor.googleauthorKyeong-Mee Park-
dc.contributor.googleauthorHyun Sil Kim-
dc.contributor.googleauthorKee-Deog Kim-
dc.contributor.googleauthorWonse Park-
dc.identifier.doi10.1155/2017/6087676-
dc.contributor.localIdA00332-
dc.contributor.localIdA01121-
dc.contributor.localIdA01589-
dc.contributor.localIdA03692-
dc.contributor.localIdA05440-
dc.relation.journalcodeJ00315-
dc.identifier.eissn2314-6141-
dc.identifier.pmid28280735-
dc.contributor.alternativeNameKim, Kee Deog-
dc.contributor.alternativeNameKim, Hyun Sil-
dc.contributor.alternativeNamePark, Wonse-
dc.contributor.alternativeNameJung, Ui Won-
dc.contributor.alternativeNameHuh, Jisun-
dc.contributor.affiliatedAuthorKim, Kee Deog-
dc.contributor.affiliatedAuthorKim, Hyun Sil-
dc.contributor.affiliatedAuthorPark, Wonse-
dc.contributor.affiliatedAuthorJung, Ui Won-
dc.contributor.affiliatedAuthorHuh, Jisun-
dc.citation.volume2017-
dc.citation.startPage6087676-
dc.identifier.bibliographicCitationBioMed Research International, Vol.2017 : 6087676, 2017-
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Advanced General Dentistry (통합치의학과) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Oral Pathology (구강병리학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실) > 1. Journal Papers

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