Cited 3 times in
Safety and Efficacy of Uterine Artery Embolization in Ectopic Pregnancies Refractory to Systemic Methotrexate Treatment: A Single-Center Study
DC Field | Value | Language |
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dc.contributor.author | 권준호 | - |
dc.contributor.author | 김경민 | - |
dc.contributor.author | 김만득 | - |
dc.contributor.author | 원종윤 | - |
dc.contributor.author | 이도연 | - |
dc.contributor.author | 한기창 | - |
dc.date.accessioned | 2018-07-20T08:03:28Z | - |
dc.date.available | 2018-07-20T08:03:28Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 0174-1551 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/160793 | - |
dc.description.abstract | BACKGROUND: To investigate the use of uterine artery embolization (UAE) to manage ectopic pregnancies that are refractory to systemic methotrexate (MTX) therapy and plagued by persistently high serum β-human chorionic gonadotrophin (hCG) levels and vaginal bleeding. The safety and efficacy of UAE were addressed. MATERIALS AND METHODS: A retrospective review was conducted for thirteen patients (mean age 35.2 years; range 28-41 years), who were treated between December 2006 and June 2016. Each was subjected to UAE due to persistently high serum β-hCG levels and vaginal bleeding after systemic MTX therapy for ectopic pregnancy. Embolic agents used were non-spherical polyvinyl alcohol or gelatin sponge particles. Post-treatment follow-up was performed by monitoring for clinical signs of vaginal bleeding, serum β-hCG testing, and transvaginal US. Outcomes were technical success, clinical success, and complications. RESULTS: Median follow-up period was 172.5 days (range 30-600 days). Technical success was achieved in all 13 patients (100%). In 10 patients, vaginal bleeding resolved after one UAE attempt (clinical success 76.0%). Rebleeding in other three (23.1%) was controlled through repeat UAE. Seven patients (53.8%) had additional dilatation and curettage to remove gestational sac remnants. All ectopic pregnancies were successfully treated by UAE, with normalization of serum β-hCG levels during follow-up monitoring (P = 0.01). Uterine preservation was achieved in all 13 patients, without major procedural complications. CONCLUSION: UAE appears safe and effective as treatment of ectopic pregnancies marked by persistently high serum β-hCG levels and vaginal bleeding after systemic MTX treatment. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Springer Verlag | - |
dc.relation.isPartOf | CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Chorionic Gonadotropin/blood | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Pregnancy | - |
dc.subject.MESH | Pregnancy, Ectopic/blood | - |
dc.subject.MESH | Pregnancy, Ectopic/therapy* | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Treatment Failure | - |
dc.subject.MESH | Uterine Artery Embolization/adverse effects | - |
dc.subject.MESH | Uterine Artery Embolization/methods* | - |
dc.subject.MESH | Uterine Hemorrhage/therapy | - |
dc.title | Safety and Efficacy of Uterine Artery Embolization in Ectopic Pregnancies Refractory to Systemic Methotrexate Treatment: A Single-Center Study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Radiology | - |
dc.contributor.googleauthor | Joon Ho Kwon | - |
dc.contributor.googleauthor | Gyoung Min Kim | - |
dc.contributor.googleauthor | Kichang Han | - |
dc.contributor.googleauthor | Man Deuk Kim | - |
dc.contributor.googleauthor | Jong Yun Won | - |
dc.contributor.googleauthor | Do Yun Lee | - |
dc.identifier.doi | 10.1007/s00270-017-1664-7 | - |
dc.contributor.localId | A05085 | - |
dc.contributor.localId | A00296 | - |
dc.contributor.localId | A00420 | - |
dc.contributor.localId | A02443 | - |
dc.contributor.localId | A02718 | - |
dc.contributor.localId | A05062 | - |
dc.relation.journalcode | J00459 | - |
dc.identifier.eissn | 1432-086X | - |
dc.identifier.pmid | 28462440 | - |
dc.identifier.url | https://link.springer.com/article/10.1007%2Fs00270-017-1664-7 | - |
dc.subject.keyword | Ectopic pregnancy | - |
dc.subject.keyword | Methotrexate | - |
dc.subject.keyword | Serum β-human chorionic gonadotrophin (hCG) | - |
dc.subject.keyword | Uterine artery embolization | - |
dc.subject.keyword | Vaginal bleeding | - |
dc.contributor.alternativeName | Kwon, Joon Ho | - |
dc.contributor.alternativeName | Kim, Gyoung Min | - |
dc.contributor.alternativeName | Kim, Man Deuk | - |
dc.contributor.alternativeName | Won, Jong Yun | - |
dc.contributor.alternativeName | Lee, Do Yun | - |
dc.contributor.alternativeName | Han, Ki Chang | - |
dc.contributor.affiliatedAuthor | Kwon, Joon Ho | - |
dc.contributor.affiliatedAuthor | Kim, Gyoung Min | - |
dc.contributor.affiliatedAuthor | Kim, Man Deuk | - |
dc.contributor.affiliatedAuthor | Won, Jong Yun | - |
dc.contributor.affiliatedAuthor | Lee, Do Yun | - |
dc.contributor.affiliatedAuthor | Han, Ki Chang | - |
dc.citation.volume | 40 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 1351 | - |
dc.citation.endPage | 1357 | - |
dc.identifier.bibliographicCitation | CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, Vol.40(9) : 1351-1357, 2017 | - |
dc.identifier.rimsid | 60678 | - |
dc.type.rims | ART | - |
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