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Advanced Colonic Neoplasia at Follow-up Colonoscopy According to Risk Components and Adenoma Location at Index Colonoscopy: A Retrospective Study of 1,974 Asymptomatic Koreans

DC FieldValueLanguage
dc.contributor.author박유미-
dc.contributor.author박재준-
dc.contributor.author박효진-
dc.contributor.author백수정-
dc.contributor.author이혜선-
dc.contributor.author조소영-
dc.date.accessioned2018-07-20T07:57:58Z-
dc.date.available2018-07-20T07:57:58Z-
dc.date.issued2017-
dc.identifier.issn1976-2283-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/160714-
dc.description.abstractBackground/Aims: We aimed to estimate the cumulative incidence of advanced colonic neoplasia and analyze the risk factors for advanced colonic neoplasia according to risk components and adenoma location at index colonoscopy. Methods: We reviewed 1,974 subjects who underwent a follow-up colonoscopy after a complete screening colonoscopy and the removal of all polyps. We estimated the cumulative incidence of a subsequent advanced neoplasia according to risk groups (normal, low-risk, and high-risk). Risk factors were analyzed by risk components (≥3 adenomas, adenoma ≥1 cm, and villous-type adenoma) and adenoma location. Results: Overall, 111 advanced neoplasias (5.6%) were newly diagnosed at the follow-up colonoscopy. The 3-year cumulative incidences of advanced neoplasia were 0.8%, 3.1%, and 10.2% in the normal, low-risk, and high-risk groups, respectively (p<0.0001), and the 5-year cumulative incidences were 2.2%, 8.6%, and 20.2%, respectively (p<0.0001). Age ≥60 years (hazard ratio [HR], 1.78; 95% confidence interval [CI], 1.21 to 2.63), right-sided colonic adenoma (HR, 1.74; 95% CI, 1.13 to 2.66), ≥3 adenomas (HR, 2.00; 95% CI, 1.22 to 3.28), and adenomas ≥1 cm in size (HR, 2.03; 95% CI, 1.20 to 3.44) in the index colonoscopy were independent risk factors for subsequent development of advanced neoplasia. Conclusions: Right-sided colonic adenoma, ≥3 adenomas, adenomas ≥1 cm, and age ≥60 years at the index colonoscopy were significant risk factors for advanced neoplasia following a complete screening colonoscopy and removal of all polyps.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherEditorial Office of Gut and Liver-
dc.relation.isPartOfGUT AND LIVER-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdenoma/epidemiology-
dc.subject.MESHAdenoma/etiology-
dc.subject.MESHAdenoma/pathology*-
dc.subject.MESHAsymptomatic Diseases-
dc.subject.MESHColon/pathology-
dc.subject.MESHColon/surgery-
dc.subject.MESHColonic Neoplasms/epidemiology-
dc.subject.MESHColonic Neoplasms/etiology-
dc.subject.MESHColonic Neoplasms/pathology*-
dc.subject.MESHColonic Polyps/complications*-
dc.subject.MESHColonic Polyps/surgery-
dc.subject.MESHColonoscopy/methods*-
dc.subject.MESHEarly Detection of Cancer/methods-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHIncidence-
dc.subject.MESHMale-
dc.subject.MESHMass Screening/methods-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPostoperative Complications-
dc.subject.MESHProportional Hazards Models-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Assessment-
dc.subject.MESHRisk Factors-
dc.titleAdvanced Colonic Neoplasia at Follow-up Colonoscopy According to Risk Components and Adenoma Location at Index Colonoscopy: A Retrospective Study of 1,974 Asymptomatic Koreans-
dc.typeArticle-
dc.contributor.collegeOthers-
dc.contributor.departmentGangnam Severance Hospital-
dc.contributor.googleauthorSu Jung Baik-
dc.contributor.googleauthorHyojin Park-
dc.contributor.googleauthorJae Jun Park-
dc.contributor.googleauthorHyun Ju Lee-
dc.contributor.googleauthorSo Young Jo-
dc.contributor.googleauthorYoo Mi Park-
dc.contributor.googleauthorHye Sun Lee-
dc.identifier.doi10.5009/gnl16402-
dc.contributor.localIdA04937-
dc.contributor.localIdA01636-
dc.contributor.localIdA01774-
dc.contributor.localIdA04580-
dc.contributor.localIdA03312-
dc.contributor.localIdA05419-
dc.relation.journalcodeJ00954-
dc.identifier.eissn2005-1212-
dc.identifier.pmid28750483-
dc.subject.keywordColonic neoplasms-
dc.subject.keywordColonoscopy-
dc.subject.keywordEarly detection of cancer-
dc.contributor.alternativeNamePark, Yoo Mi-
dc.contributor.alternativeNamePark, Jae Jun-
dc.contributor.alternativeNamePark, Hyo Jin-
dc.contributor.alternativeNameBaik, Su Jung-
dc.contributor.alternativeNameLee, Hye Sun-
dc.contributor.alternativeNameJo, So Young-
dc.contributor.affiliatedAuthorPark, Yoo Mi-
dc.contributor.affiliatedAuthorPark, Jae Jun-
dc.contributor.affiliatedAuthorPark, Hyo Jin-
dc.contributor.affiliatedAuthorBaik, Su Jung-
dc.contributor.affiliatedAuthorLee, Hye Sun-
dc.contributor.affiliatedAuthorJo, So Young-
dc.citation.volume11-
dc.citation.number5-
dc.citation.startPage667-
dc.citation.endPage673-
dc.identifier.bibliographicCitationGUT AND LIVER, Vol.11(5) : 667-673, 2017-
dc.identifier.rimsid43777-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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