0 224

Cited 8 times in

Changes in choroidal thickness after vitrectomy for epiretinal membrane combined with vitreomacular traction

 Eui Chun Kang  ;  Kyou Ho Lee  ;  Hyoung Jun Koh 
 ACTA OPHTHALMOLOGICA, Vol.95(5) : e393-e398, 2017 
Journal Title
Issue Date
Aged ; Choroid/pathology* ; Epiretinal Membrane/diagnosis ; Epiretinal Membrane/surgery* ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Postoperative Period ; Retrospective Studies ; Time Factors ; Tomography, Optical Coherence/methods* ; Treatment Outcome ; Vitrectomy/methods*
choroidal thickness ; epiretinal membrane ; vitrectomy ; vitreomacular traction
PURPOSE: To compare choroidal thickness after vitrectomy between epiretinal membrane (ERM) with and without vitreomacular traction (VMT). METHODS: In this retrospective study, 228 consecutive participants with ERM who underwent vitrectomy were categorized into two groups according to the presence of VMT on spectral domain-optical coherence tomography: VMT group (ERM with VMT, n = 21) and non-VMT group (ERM without VMT, n = 207). The primary outcome was the mean subfoveal choroidal thickness (SFCT) at baseline, and at 3 and 6 months postsurgery. RESULTS: At baseline, the prevalence of VMT in eyes with ERM was 9.6% (21/228), and mean SFCT was greater in the VMT than in the non-VMT group (270.3 ± 93.4 vs. 223.7 ± 82.1 μm; p = 0.015). After surgery, mean SFCT decreased in the VMT group (241.7 ± 92.3 μm at 3 months and 228.8 ± 86.4 μm at 6 months; p < 0.001), but remained unchanged in the non-VMT group (223.6 ± 78.9 μm at 3 months and 223.3 ± 82.6 μm at 6 months; p = 0.696). There were no differences in mean SFCT between the groups at 3 and 6 months after surgery (p = 0.339 and p = 0.772, respectively). CONCLUSION: Choroidal thickness was greater in ERM eyes with than without VMT possibly due to direct anteroposterior traction on the retina and choroid, increased vascular endothelial growth factor associated with stress on retinal pigment epithelial cells and inflammation. After vitrectomy, mean SFCT reduced in the eyes with VMT, but not in those without VMT.
Full Text
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Eui Chun(강의천)
Koh, Hyoung Jun(고형준) ORCID logo https://orcid.org/0000-0002-5932-8516
Lee, Kyou Ho(이규호)
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.