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PI-RADS version 2: Preoperative role in the detection of normal-sized pelvic lymph node metastasis in prostate cancer

DC Field Value Language
dc.contributor.author나군호-
dc.contributor.author박성윤-
dc.contributor.author신수진-
dc.contributor.author오영택-
dc.contributor.author정대철-
dc.contributor.author조남훈-
dc.contributor.author최영득-
dc.contributor.author홍성준-
dc.date.accessioned2018-07-20T07:49:07Z-
dc.date.available2018-07-20T07:49:07Z-
dc.date.issued2017-
dc.identifier.issn0720-048X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/160552-
dc.description.abstractOBJECTIVES: To analyze whether Prostate Imaging Reporting and Data System (PI-RADSv2) scores are associated with a risk of normal-sized pelvic lymph node metastasis (PLNM) in prostate cancer (PCa). MATERIALS AND METHODS: A consecutive series of 221 patients who underwent magnetic resonance imaging and radical prostatectomy with pelvic lymph node dissection (PLND) for PCa were retrospectively analyzed under the approval of institutional review board in our institution. No patients had enlarged (≥0.8cm in short-axis diameter) lymph nodes. Clinical parameters [prostate-specific antigen (PSA), greatest percentage of biopsy core, and percentage of positive cores], and PI-RADSv2 score from two independent readers were analyzed with multivariate logistic regression and receiver operating-characteristic curve for PLNM. Diagnostic performance of PI-RADSv2 and Briganti nomogram was compared. Weighted kappa was investigated regarding PI-RADSv2 scoring. RESULTS: Normal-sized PLNM was found in 9.5% (21/221) of patients. In multivariate analysis, PI-RADSv2 (reader 1, p=0.009; reader 2, p=0.026) and PSA (reader 1, p=0.008; reader 2, p=0.037) were predictive of normal-sized PLNM. Threshold of PI-RADSv2 was a score of 5, where PI-RADSv2 was associated with high sensitivity (reader 1, 95.2% [20/21]; reader 2, 90.5% [19/21]) and negative predictive value (reader 1, 99.2% [124/125]; reader 2, 98.6% [136/138]). However, diagnostic performance of PI-RADSv2 (AUC=0.786-0.788) was significantly lower than that of Briganti nomogram (AUC=0.890) for normal-sized PLNM (p<0.05). The inter-reader agreement was excellent for PI-RADSv2 of 5 or not (weighted kappa=0.804). CONCLUSION: PI-RADSv2 scores may be associated with the risk of normal-sized PLNM in PCa.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherElsevier Science Ireland Ltd-
dc.relation.isPartOfEUROPEAN JOURNAL OF RADIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHBiopsy, Large-Core Needle-
dc.subject.MESHHumans-
dc.subject.MESHLymph Node Excision-
dc.subject.MESHLymph Nodes/diagnostic imaging*-
dc.subject.MESHLymph Nodes/pathology-
dc.subject.MESHLymph Nodes/surgery-
dc.subject.MESHLymphatic Metastasis-
dc.subject.MESHMagnetic Resonance Imaging/methods-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPelvis-
dc.subject.MESHPreoperative Care/methods*-
dc.subject.MESHProstate/diagnostic imaging-
dc.subject.MESHProstate/pathology-
dc.subject.MESHProstate/surgery-
dc.subject.MESHProstatectomy-
dc.subject.MESHProstatic Neoplasms/diagnostic imaging*-
dc.subject.MESHProstatic Neoplasms/pathology*-
dc.subject.MESHProstatic Neoplasms/surgery-
dc.subject.MESHRadiology Information Systems*-
dc.subject.MESHRetrospective Studies-
dc.titlePI-RADS version 2: Preoperative role in the detection of normal-sized pelvic lymph node metastasis in prostate cancer-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Urology-
dc.contributor.googleauthorSung Yoon Park-
dc.contributor.googleauthorSu-Jin Shin-
dc.contributor.googleauthorDae Chul Jung-
dc.contributor.googleauthorNam Hoon Cho-
dc.contributor.googleauthorYoung Deuk Choi-
dc.contributor.googleauthorKoon Ho Rha-
dc.contributor.googleauthorSung Joon Hong-
dc.contributor.googleauthorYoung Taik Oh-
dc.identifier.doi10.1016/j.ejrad.2017.03.009-
dc.contributor.localIdA01227-
dc.contributor.localIdA01509-
dc.contributor.localIdA04596-
dc.contributor.localIdA02390-
dc.contributor.localIdA03592-
dc.contributor.localIdA03812-
dc.contributor.localIdA04111-
dc.contributor.localIdA04402-
dc.relation.journalcodeJ00845-
dc.identifier.eissn1872-7727-
dc.identifier.pmid28629566-
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0720048X17301092-
dc.subject.keywordLymph node-
dc.subject.keywordMRI-
dc.subject.keywordPI-RADS-
dc.subject.keywordProstate cancer-
dc.contributor.alternativeNameRha, Koon Ho-
dc.contributor.alternativeNamePark, Sung Yoon-
dc.contributor.alternativeNameShin, Su Jin-
dc.contributor.alternativeNameOh, Young Taik-
dc.contributor.alternativeNameJung, Dae Chul-
dc.contributor.alternativeNameCho, Nam Hoon-
dc.contributor.alternativeNameChoi, Young Deuk-
dc.contributor.alternativeNameHong, Sung Joon-
dc.contributor.affiliatedAuthorRha, Koon Ho-
dc.contributor.affiliatedAuthorPark, Sung Yoon-
dc.contributor.affiliatedAuthorShin, Su Jin-
dc.contributor.affiliatedAuthorOh, Young Taik-
dc.contributor.affiliatedAuthorJung, Dae Chul-
dc.contributor.affiliatedAuthorCho, Nam Hoon-
dc.contributor.affiliatedAuthorChoi, Young Deuk-
dc.contributor.affiliatedAuthorHong, Sung Joon-
dc.citation.volume91-
dc.citation.startPage22-
dc.citation.endPage28-
dc.identifier.bibliographicCitationEUROPEAN JOURNAL OF RADIOLOGY, Vol.91 : 22-28, 2017-
dc.identifier.rimsid44787-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers

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