0 64

Cited 3 times in

Association between Previous Cataract Surgery and Age-Related Macular Degeneration

 Tyler Hyungtaek Rim  ;  Christopher Seungkyu Lee  ;  Sung Chul Lee  ;  Sangah Kim  ;  Sung Soo Kim  ;  Epidemiologic Survey Committee of the Korean  ;  Ophthalmological Society 
 Seminars in Ophthalmology, Vol.32(4) : 466-473, 2017 
Journal Title
 Seminars in Ophthalmology 
Issue Date
Adult ; Cataract/epidemiology ; Cataract Extraction/adverse effects* ; Cross-Sectional Studies ; Female ; Follow-Up Studies ; Humans ; Macular Degeneration/diagnosis ; Macular Degeneration/epidemiology* ; Macular Degeneration/etiology ; Male ; Middle Aged ; Nutrition Surveys ; Prevalence ; Republic of Korea/epidemiology ; Retrospective Studies ; Risk Factors ; Time Factors ; Visual Acuity*
Age-related macular degeneration ; KNHANES ; cataract ; cataract surgery ; national survey
PURPOSE: To assess the association between age-related macular degeneration (AMD) and previous cataract surgery. METHODS: We studied 17,987 randomly selected participants from the Korea National Health and Nutrition Examination Survey who were aged ≥40 years and underwent additional ophthalmologic examinations in 2008‒12. The associations between previous cataract surgery and early/late AMD were identified using multivariate logistic regression analysis of data from right or left eyes. Clustered multivariate logistic regression analysis was performed using both eyes to assess inter-eye correlation in same subject. Previous cataract surgery and cataract subtypes were based on slit-lamp examination without pupil dilation. Early and late AMD diagnoses were based on non-mydriatic digital retinal image. RESULTS: By univariate logistic regression, both early and late AMD prevalence were higher in subjects with pseudophakia/aphakia compared to subjects with cataract as a reference group, or subjects with phakic eye (including clear lens) as a reference group. In univariate logistic regression, both early and late AMD prevalence were higher in eyes with cataract or pseudo/aphakia compared to eyes with clear lens. However, after adjusting for age with multivariate logistic regression, all statistically significant differences in AMD prevalence among subgroups disappeared. CONCLUSIONS: We found no association between the previous cataract surgery and increased early/late AMD risk in our representative, large, national patient database. This suggests that increasing age, and not cataract surgery history, is predictive of AMD risk. These findings are limited by cross-sectional study and need to be replicated by other longitudinal observational studies.
Full Text
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
김상아(Kim, Sangah) ORCID logo https://orcid.org/0000-0002-8511-2903
김성수(Kim, Sung Soo) ORCID logo https://orcid.org/0000-0002-0574-7993
이성철(Lee, Sung Chul) ORCID logo https://orcid.org/0000-0001-9438-2385
이승규(Lee, Christopher Seungkyu) ORCID logo https://orcid.org/0000-0001-5054-9470
임형택(Rim, Tyler Hyungtaek)
RIS (EndNote)
XLS (Excel)
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.