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Effect of obesity on functional outcomes at 6months post-stroke among elderly Koreans: a prospective multicentre study

 Shin Yi Jang  ;  Yong-Il Shin  ;  Deog Young Kim  ;  Min Kyun Sohn  ;  Jongmin Lee  ;  Sam-Gyu Lee  ;  Gyung-Jae Oh  ;  Yang-Soo Lee  ;  Min Cheol Joo  ;  Eun Young Han  ;  Won Hyuk Chang  ;  Chung Kang  ;  Yun-Hee Kim 
 BMJ Open, Vol.5(12) : e008712, 2015 
Journal Title
 BMJ Open 
Issue Date
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Body Mass Index ; Female ; Follow-Up Studies ; Humans ; Linear Models ; Male ; Middle Aged ; Obesity/complications* ; Obesity/diagnosis ; Prospective Studies ; Recovery of Function* ; Republic of Korea ; Risk Factors ; Stroke/complications ; Stroke Rehabilitation* ; Young Adult
body mass index ; elderly ; functional independence measure ; ischemic stroke ; obese
Objectives : We examined whether obesity based on body mass index (BMI) was a predictor of functional independence measure (FIM) at 6 months after ischaemic stroke onset while adjusting for stroke risk factors and covariates and stratifying by age group. Design : This is an interim report of the Korean Stroke Cohort for Functioning and Rehabilitation that was designed as a nested case study within a nationwide hospital-based cohort. Setting : We identified all patients who were admitted to nine representative hospitals in Korea from 2012 until 2014 under a diagnosis of acute first-ever ischaemic stroke. The hospitals were selected from the metropolitan district, mid-sized cities and a small-sized city. Participants : The sample included 2057 patients with acute ischaemic stroke who were at least 18 years old. Primary and secondary outcome measures : We divided participants into two age levels (<65 and ≥65 years). Participants were classified into five groups according to their baseline BMI at admission: underweight (BMI<18.5), normal (18.5≤BMI<23), overweight (23≤BMI<25), obese (25≤BMI<30) and extremely obese (30≤BMI). Results : The proportion of patients who were aged ≥65 years was 55.0%. The proportions of underweight, normal, overweight, obese and extremely obese patients were 2.6%, 24.3%, 29.6%, 37.2% and 6.3%, respectively, in the <65 years group and 5.5%, 34.5%, 27.9%, 28.8% and 3.3%, respectively, in the ≥65 years group. In a multiple linear regression, the 6-month FIM after stroke in the elderly group was significantly associated with being extremely obese (7.95, p<0.05) after adjusting for confounding variables. In the <65 years group, the 6-month FIM was not associated with any weight category. Conclusions : This nationwide hospital-based cohort study showed that extreme obesity is a predictor of a good 6-month FIM, especially in patients with ischaemic stroke who are at least 65 years of age.
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1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers
Yonsei Authors
김덕용(Kim, Deog Young) ORCID logo https://orcid.org/0000-0001-7622-6311
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