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Correlation Between Timed Barium Esophagogram and Esophageal Transit Scintigraphy Results in Achalasia

 Yoo Mi Park  ;  Han Ho Jeon  ;  Jae Jun Park  ;  Jie-Hyun Kim  ;  Young Hoon Youn  ;  Hyojin Park 
 DIGESTIVE DISEASES AND SCIENCES, Vol.60(8) : 2390-2397, 2015 
Journal Title
Issue Date
Adult ; Barium Sulfate* ; Contrast Media*/administration & dosage ; Esophageal Achalasia/diagnosis* ; Esophageal Achalasia/diagnostic imaging ; Esophageal Achalasia/physiopathology ; Female ; Humans ; Male ; Manometry ; Middle Aged ; Radiography ; Retrospective Studies
Achalasia ; Manometry ; Timed barium esophagogram ; Esophageal transit scintigraphy
BACKGROUND: Timed barium esophagogram (TBE) and esophageal transit scintigraphy (ETS) have been adopted as useful ways to evaluate achalasia patients. TBE has merit as a simple, non-invasive, and convenient method.

AIMS: The study sought to compare the results of these two tests and verify their usefulness in evaluating treatment response. In addition, we assessed whether TBE could effectively replace ETS through correlation analysis.

METHODS: The medical records of 50 achalasia patients treated between September 2011 and June 2014 were reviewed retrospectively. The height and width of the barium column at 1, 2, and 5 min were measured by TBE. Half-life (T 1/2, min) and R 30 (percentage of remaining radioactivity 30 s after radioisotope ingestion) were measured by ETS. Both tests were performed before and after treatment, and the tests were carried out 1 and 2 days after procedures. And we analyzed the correlation between the parameters from the two tests.

RESULTS: The parameters of TBE and ETS were improved after treatment (p < 0.05). Before treatment, the height and width results at 5 min from TBE positively correlated with the T 1/2 parameter from ETS (correlation coefficients of 0.59 and 0.75, respectively). After treatment, the correlation coefficients between the 5-min height and width of the barium column by TBE and T 1/2 by ETS were 0.55 and 0.46, respectively.

CONCLUSIONS: Both TBE and ETS are useful modalities in assessing esophageal emptying and response to achalasia treatment. TBE and ETS results have a statistically significant correlation both pre- and post-treatment. We suggest that TBE could effectively replace ETS for the assessment of achalasia.
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6. Others (기타) > Gangnam Severance Hospital Health Promotion Center(강남세브란스병원 체크업) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jie-Hyun(김지현) ORCID logo https://orcid.org/0000-0002-9198-3326
Park, Yoo Mi(박유미) ORCID logo https://orcid.org/0000-0002-3642-7300
Park, Jae Jun(박재준)
Park, Hyo Jin(박효진) ORCID logo https://orcid.org/0000-0003-4814-8330
Youn, Young Hoon(윤영훈) ORCID logo https://orcid.org/0000-0002-0071-229X
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