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굴절수술 후 잔여 근시에 대한 보강수술로서 각막표면연마굴절수술과 마이토마이신의 효과

Other Titles
 Surface Ablation with 0.02% Mitomycin C for Retreatment after LASIK and LASEK 
 김강윤  ;  김홍석  ;  정지원  ;  이형근  ;  서경률  ;  김응권  ;  김태임 
 Journal of the Korean Ophthalmological Society (대한안과학회지), Vol.56(7) : 992-997, 2015 
Journal Title
 Journal of the Korean Ophthalmological Society (대한안과학회지) 
Issue Date
LASEK ; LASIK ; Mitomycin C ; Retreatment ; Surface ablation
Purpose : To evaluate the efficacy and safety of surface ablation with mitomycin C (MMC) for the retreatment of refractive errors following laser-assisted in-situ keratomileusis (LASIK) and laser-assisted sub-epithelial keratectomy (LASEK). Methods : In this retrospective clinical study conducted at a single center, we evaluated 23 eyes that received surface ablation with MMC (0.02%, 20 seconds) between 2009 and 2013 for the treatment of residual refractive errors following myopic LASIK and LASEK. All eyes were evaluated for corneal thickness, initial refractive error, time interval to retreatment, amount of retreatment, duration of postoperative topical steroids use as well as uncorrected vision, spherical equivalent and corneal haziness preoperatively and 1, 3, 6 and 12 months postoperatively. Results : Initially corrected myopia in the LASIK group was -6.47 ± 2.17 D and -5.68 ± 2.51 D in the LASEK group. Mean time between initial and retreatment by surface ablation was 11.88 ± 5.59 months for LASIK and 14.07 ± 10.10 for LASEK. Retreat amount was 1.49 ± 0.36 D after LASIK and -1.65 ± 0.41 D after LASEK. At postoperative 12 months, uncorrected visions were -0.061 ± 0.886 (log MAR) in the LASIK group and -0.004 ± 0.745 (log MAR) in the LASEK group and spherical equivalents were -0.55 ± 0.56 D in the LASIK group and 0.36 ± 0.33 D in the LASEK group. Postoperative hazes developed in 1 of 8 LASIK eyes and 3 of 15 LASEK eyes which resolved with application of topical steroid for 2-3 months postoperatively. Conclusions : Surface ablation with 0.02% MMC is safe and highly effective for treating myopic regression following LASIK or LASEK. Application of 0.02% MMC for 20 seconds was effective in preventing postoperative haze formation and maintaining stable vision and spherical equivalent at 12 months after retreatment.
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1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kang Yoon(김강윤)
Kim, Eung Kweon(김응권) ORCID logo https://orcid.org/0000-0002-1453-8042
Kim, Tae Im(김태임) ORCID logo https://orcid.org/0000-0001-6414-3842
Seo, Kyuong Yul(서경률) ORCID logo https://orcid.org/0000-0002-9855-1980
Lee, Hyung Keun(이형근) ORCID logo https://orcid.org/0000-0002-1123-2136
Jung, Ji Won(정지원)
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