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Anxiety and depressive symptoms among patients infected with human immunodeficiency virus in South Korea

 Mee-Kyung Kee  ;  Sae-Young Lee  ;  Na-Young Kim  ;  Joo-Shil Lee  ;  June Myung Kim  ;  Jun Yong Choi  ;  Nam Su Ku  ;  Moon Won Kang  ;  Min Ja Kim  ;  Jun Hee Woo  ;  Shin-Woo Kim  ;  Joon Young Song  ;  Ji-Hyeon Baek  ;  Bo Youl Choi  ;  Sung Soon Kim 
 AIDS Care, Vol.27(9) : 1174-1182, 2015 
Journal Title
 AIDS Care 
Issue Date
Adult ; Cohort Studies ; Depressive Disorder/epidemiology* ; Disease Progression ; Female ; HIV Infections/psychology* ; Humans ; Male ; Odds Ratio ; Prevalence ; Psychiatric Status Rating Scales ; Republic of Korea/epidemiology ; Sexual Partners ; Surveys and Questionnaires
HIV-infected patients ; Korea ; Korea HIV/AIDS Cohort Study ; anxiety symptom ; depressive symptom
Patients infected with human immunodeficiency virus (HIV) may develop mental health problems such as anxiety and depression, which negatively impact of disease progression. We investigated factors associated with the prevalence of anxiety and depression symptoms among HIV-infected patients in Korea. A total of 840 HIV-infected patients who participated in the Korea HIV/AIDS Cohort Study from 2006 to 2012 were evaluated. Socio-demographic, epidemiologic, and clinical variables were obtained through standardized questionnaires. The State-Trait Anxiety Inventory and Beck Depression Inventory were used to assess the symptoms of anxiety and depression. Multiple logistic regression analyses were performed to identify factors associated with symptoms of anxiety and depression. The prevalence of anxiety and depressive symptoms among HIV-infected patients was 32% and 36%, respectively. Ex-smoker and persistent symptoms for more than one week within the past six months and diagnosis of HIV infection within one year were associated with increased anxiety symptoms (odds ratio [OR] 1.71, 95% confidence interval [CI] 1.09-2.69; OR 1.52, 95% CI 1.09-2.11; OR 1.49, 95% CI 1.02-2.20) and current smoking and persistent symptoms were also associated with increased depressive symptoms (OR 2.10, 95% CI 1.31-3.30; OR 1.87, 95% CI 1.25-2.79). Marital status, current smoking, current drinking, and persistent symptoms were associated with both increased anxiety and depressive symptoms (OR 1.75, 95% CI 1.07-2.88; OR 1.66, 95% CI 1.06-2.61; OR 1.88, 95% CI 1.18-2.99). The prevalence of anxiety and depressive symptoms among HIV-infected patients is higher than those estimated for the general population. This study shows the necessity to evaluate symptoms of anxiety and depression and suggest psychological support for HIV-infected patients who smoke or have persistent symptoms or have sexual partner or drink.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
구남수(Ku, Nam Su) ORCID logo https://orcid.org/0000-0002-9717-4327
김준명(Kim, June Myung)
최준용(Choi, Jun Yong) ORCID logo https://orcid.org/0000-0002-2775-3315
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