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주요우울장애환자에서 생애초기스트레스경험이 얼굴정서자극에 대한 반응에 미치는 영향

Other Titles
 Effect of Early Life Stress on Response to Emotional Facial Stimuli in Patients with Major Depressive Disorder 
Authors
 송어진  ;  최원정  ;  오지희  ;  차샛별  ;  석정호 
Citation
 Journal of Korean Society for Depressive and Bipolar Disorders (우울ㆍ조울병), Vol.13(3) : 111-119, 2015 
Journal Title
 Journal of Korean Society for Depressive and Bipolar Disorders (우울ㆍ조울병) 
ISSN
 1738-0960 
Issue Date
2015
Keywords
Early-life stress ; Major depressive disorder ; Emotional reactivity ; Negativity bias ; Abuse ; Neglect
Abstract
Objectives : The aim of this study is to investigate the effect of Early-life stress (ELS) including direct abuse(physical, emotional, sexual abuse) and indirect abuse (neglect) on response to emotional faces in the patients with major depressive disorder (MDD). Methods : The participants were 21 patients with MDD and 23 healthy volunteers. Subjects were assessed concerning ELS, depressive symptom severity with self-report questionnaires. We developed an experimental task using emotional facial stimuli. The response characteristics of the MDD patients with ELS in four emotional conditions (positive, negative, neutral, combined) were compared with the patient without ELS and healthy control groups. Results : There were significant effects of neglect in the neutral emotional task condition. MDD patients with neglect responded more negatively to neutral facial stimuli than the patient control and the healthy control groups. The MDD patient with direct abuse chose higher unpleasant response in neutral/pleasant condition than the patient control and the healthy control groups. In correlation analysis abuses and severity of depression correlated significantly with negatively biased response rate in neutral condition. Conclusion : We found that ELS experiences might be a significant risk factor for pathological negativity bias in patients with MDD especially in the neutral and ambivalent emotional condition
DOI
2015
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
5. Research Institutes (연구소) > Institute of Behavioral Sciences in Medicine (의학행동과학연구소) > 1. Journal Papers
Yonsei Authors
Seok, Jeong Ho(석정호) ORCID logo https://orcid.org/0000-0002-9402-7591
Song, Eu-Jin(송어진)
Cha, Saet Byeol(차샛별)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/156934
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