Adult ; Aged ; Aged, 80 and over ; Asthma/epidemiology ; Cataract/epidemiology* ; Comorbidity ; Cross-Sectional Studies ; Dermatitis, Atopic/epidemiology ; Diabetes Mellitus/epidemiology ; Female ; Health Behavior* ; Health Surveys ; Humans ; Hypertension/epidemiology ; Logistic Models ; Male ; Middle Aged ; Nomograms ; Odds Ratio ; Population Surveillance/methods* ; Prevalence ; Republic of Korea/epidemiology ; Residence Characteristics ; Risk Factors ; Self Report ; Sleep ; Socioeconomic Factors ; Surveys and Questionnaires
Keywords
Cataract ; a community health survey ; nomogram ; risk factor
Abstract
PURPOSE: To investigate sociodemographic factors, health behaviors, and comorbidities associated with cataracts in a large, nationally representative Korean sample.
MATERIALS AND METHODS: This cross-sectional study included 715554 adults aged 40 years or older who participated in the 2008-2012 Community Health Survey. Significant risk factors were identified using multivariate logistic regression analysis for self-reported cataract, and a nomogram for analysis of cataract risk was generated.
RESULTS: Roughly 11% of participants (n=88464) reported being diagnosed with cataracts by a doctor. Age was the most important independent risk factor [adjusted odds ratio (aOR)=1.11, 99% confidence interval (CI), 1.11-1.11 for each increasing year]. Significant comorbidities with descending order of effect size (aOR, 99% CI), included diabetes mellitus (1.78, 1.71-1.85), osteoporosis (1.62, 1.56-1.69), arthritis (1.54, 1.48-1.59), hepatitis B infection (1.46, 1.31-1.63), atopic dermatitis (1.50, 1.33-1.69), angina (1.46, 1.35-1.57), allergic rhinitis (1.45, 1.36-1.55), dyslipidemia (1.38, 1.31-1.45), asthma (1.35, 1.26-1.44), and hypertension (1.23, 1.19-1.28). Subjects who sleep less than 6 hours/day were more likely to have cataract than subjects who sleep more than 9 hours/day as a reference group (aOR=1.22, 99% CI, 1.11-1.34).
CONCLUSION: While the most important cataract risk factor was age, the ten comorbidities mentioned above were also significant risk factors. Interestingly, longer duration of sleep was associated with a protective effect against cataract development.