Cited 10 times in
Noninvasive measurement of pressure gradient across a coronary stenosis using phase contrast (PC)-MRI: A feasibility study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김중선 | - |
dc.contributor.author | 이상은 | - |
dc.contributor.author | 장혁재 | - |
dc.contributor.author | 최병욱 | - |
dc.date.accessioned | 2017-11-02T08:37:34Z | - |
dc.date.available | 2017-11-02T08:37:34Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 0740-3194 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/154688 | - |
dc.description.abstract | PURPOSE: To investigate the feasibility of blood pressure difference measurement, ΔP, across the coronary artery using phase contrast (PC)-MRI for potential noninvasive assessment of the functional significance of coronary artery stenosis. METHODS: Three-directional velocities in the coronary arteries acquired using 2D-PC-MRI were used with the Navier-Stokes equations to derive ΔP. Repeat phantom studies were performed to assess the reproducibility of flow velocity and ΔP. ΔP derived using PC-MRI (ΔPMR ) and that obtained using pressure transducer (ΔPPT ) were compared. Reproducibility of coronary flow velocity was assessed in healthy controls (n = 11). Patients with suspected coronary artery disease (n = 6) were studied to evaluate the feasibility of ΔPMR measurement across a coronary stenosis. RESULTS: Phantom: Good overall reproducibility of flow velocity and ΔP measurements and excellent correlation (ΔPMR vs ΔPPT ) was observed: intraclass correlation (ICC) of 0.95(Vz ), 0.72(Vx ), 0.73(Vy ), and 0.87(ΔPMR ) and R2 = 0.94, respectively. Human: Good reproducibility of coronary flow velocity was observed: ICC of 0.94/0.95(Vz ), 0.76/0.74(Vx ), and 0.80/0.77(Vy ) at cardiac phase 1/2. Significant (p = 0.025) increase in ΔPMR was observed in patients (6.40 ± 4.43 mmHg) versus controls (0.70 ± 0.57 mmHg). CONCLUSION: ΔPMR in the coronary arteries is feasible. Upon further validation using the invasive measure, ΔPMR has the potential for noninvasive assessment of coronary artery stenosis. Magn Reson Med 77:529-537, 2017. © 2016 International Society for Magnetic Resonance in Medicine. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Wiley | - |
dc.relation.isPartOf | MAGNETIC RESONANCE IN MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Blood Flow Velocity* | - |
dc.subject.MESH | Blood Pressure* | - |
dc.subject.MESH | Blood Pressure Determination | - |
dc.subject.MESH | Coronary Stenosis/diagnostic imaging* | - |
dc.subject.MESH | Coronary Stenosis/physiopathology* | - |
dc.subject.MESH | Feasibility Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Image Interpretation, Computer-Assisted/methods* | - |
dc.subject.MESH | Magnetic Resonance Angiography/methods* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Reproducibility of Results | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.subject.MESH | Signal Processing, Computer-Assisted | - |
dc.subject.MESH | Vascular Resistance | - |
dc.title | Noninvasive measurement of pressure gradient across a coronary stenosis using phase contrast (PC)-MRI: A feasibility study | - |
dc.type | Article | - |
dc.publisher.location | United States | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Internal Medicine | - |
dc.contributor.googleauthor | Zixin Deng | - |
dc.contributor.googleauthor | Zhaoyang Fan | - |
dc.contributor.googleauthor | Sang-Eun Lee | - |
dc.contributor.googleauthor | Christopher Nguyen | - |
dc.contributor.googleauthor | Yibin Xie | - |
dc.contributor.googleauthor | Jianing Pang | - |
dc.contributor.googleauthor | Xiaoming Bi | - |
dc.contributor.googleauthor | Qi Yang | - |
dc.contributor.googleauthor | Byoung-Wook Choi | - |
dc.contributor.googleauthor | Jung-Sun Kim | - |
dc.contributor.googleauthor | Daniel Berman | - |
dc.contributor.googleauthor | Hyuk-Jae Chang | - |
dc.contributor.googleauthor | Debiao Li | - |
dc.identifier.doi | 10.1002/mrm.26579 | - |
dc.contributor.localId | A02827 | - |
dc.contributor.localId | A03490 | - |
dc.contributor.localId | A04059 | - |
dc.contributor.localId | A00961 | - |
dc.relation.journalcode | J02179 | - |
dc.identifier.eissn | 1522-2594 | - |
dc.identifier.pmid | 28019028 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1002/mrm.26579/abstract | - |
dc.subject.keyword | coronary artery disease (CAD) | - |
dc.subject.keyword | coronary pressure gradient | - |
dc.subject.keyword | fractional flow reserve (FFR) | - |
dc.subject.keyword | magnetic resonance imaging (MRI) | - |
dc.subject.keyword | phase-contrast MRI (PC-MRI) | - |
dc.subject.keyword | relative pressure difference estimation | - |
dc.contributor.alternativeName | Kim, Jung Sun | - |
dc.contributor.alternativeName | Lee, Sang Eun | - |
dc.contributor.alternativeName | Chang, Hyuck Jae | - |
dc.contributor.alternativeName | Choi, Byoung Wook | - |
dc.contributor.affiliatedAuthor | Lee, Sang Eun | - |
dc.contributor.affiliatedAuthor | Chang, Hyuck Jae | - |
dc.contributor.affiliatedAuthor | Choi, Byoung Wook | - |
dc.contributor.affiliatedAuthor | Kim, Jung Sun | - |
dc.citation.title | Magnetic Resonance in Medicine | - |
dc.citation.volume | 77 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 529 | - |
dc.citation.endPage | 537 | - |
dc.identifier.bibliographicCitation | MAGNETIC RESONANCE IN MEDICINE, Vol.77(2) : 529-537, 2017 | - |
dc.date.modified | 2017-11-01 | - |
dc.identifier.rimsid | 44145 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.