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Lower incidence of contrast-induced nephropathy in patients undergoing fluorescent angiography

Authors
 Ji Hwan Lee  ;  Byunghoon Chung  ;  Sung Chul Lee  ;  Sung Soo Kim  ;  Hyoung Jun Koh  ;  Christopher Seungkyu Lee 
Citation
 BMC OPHTHALMOLOGY, Vol.17(46) : 1-6, 2017 
Journal Title
 BMC OPHTHALMOLOGY 
Issue Date
2017
MeSH
Acute Kidney Injury/chemically induced ; Acute Kidney Injury/epidemiology* ; Contrast Media/adverse effects* ; Female ; Fluorescein Angiography/adverse effects* ; Fundus Oculi ; Humans ; Male ; Middle Aged ; Republic of Korea/epidemiology ; Retinal Diseases/diagnosis ; Retrospective Studies ; Risk Assessment*
Keywords
Acute kidney injury ; Contrast media ; Fluorescein angiography
Abstract
BACKGROUND: To evaluate the incidence and risk factors of contrast-induced nephropathy (CIN) in patients undergoing fluorescein angiography (FA). METHODS: One hundred sixty patients who underwent FA as a part of ophthalmic examination and had serum creatinine (SCr) results within 24 h before FA and within 72 h after FA between 2005 and 2013 at a tertiary medical center were included. According to baseline SCr levels, the subjects were divided into low-risk group (<1.5 mg/dL), intermediate-risk group (1.5-2.0 mg/dL), and high-risk group (>2.0 mg/dL) for CIN development. The CIN incidence, and changes in renal function defined by SCr levels and estimated glomerular filtration rate (eGFR) were evaluated. Demographics and comorbidities were analyzed to investigate an association with CIN development. RESULTS: Of 160 patients, 91 were males (56.9%). The mean age was 52.46 ± 17.81 years. Two (1.3%) patients developed CIN after FA, whose SCr levels returned to normal within 10 days without hemodialysis. Overall, there were no changes before and after FA in SCr level (1.52 ± 1.31 mg/dL vs. 1.51 ± 1.28 mg/dL, respectively; p = 0.93) and eGFR (67.02 ± 36.62 mL/min/1.73 m2 vs. 66.41 ± 36.54 mL/min/1.73 m2, respectively; p = 0.54). SCr level and eGFR remained unchanged after FA in low-risk and intermediate-risk groups. In high-risk group, eGFR remined unchanged, but SCr level decreased after FA (from 3.64 ± 1.59 mg/dL to 3.53 ± 1.60 mg/dL; p = 0.04). Basline SCr and cormorbidities did not predict CIN development. CONCLUSIONS: Acute renal function deterioration was not evident in patients undergoing FA regardless of baseline renal function and comorbidities.
Files in This Item:
T201701527.pdf Download
DOI
10.1186/s12886-017-0440-4
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Koh, Hyoung Jun(고형준) ORCID logo https://orcid.org/0000-0002-5932-8516
Kim, Sung Soo(김성수) ORCID logo https://orcid.org/0000-0002-0574-7993
Lee, Sung Chul(이성철) ORCID logo https://orcid.org/0000-0001-9438-2385
Lee, Christopher Seungkyu(이승규) ORCID logo https://orcid.org/0000-0001-5054-9470
Lee, Ji Hwan(이지환)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/154373
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