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The clinical significance of accompanying NME on preoperative MR imaging in breast cancer patient

DC FieldValueLanguage
dc.contributor.author권혜미-
dc.contributor.author김정아-
dc.contributor.author손은주-
dc.contributor.author육지현-
dc.contributor.author정준-
dc.date.accessioned2017-11-02T08:15:15Z-
dc.date.available2017-11-02T08:15:15Z-
dc.date.issued2017-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/154256-
dc.description.abstractPURPOSE: To investigate the significance of accompanying NME in invasive ductal carcinoma (IDC) on preoperative MR imaging and assess the factors affecting the significance. METHODS: Between January 2015 and February 2016, 163 consecutive patients with IDC who underwent preoperative MR imaging and subsequent surgery were enrolled and reviewed. Index cancer mass size and total extent with accompanying NME on MR images was measured and compared with pathologic size. Positive NME was defined as pathological result of IDC or DCIS. To identify affecting factors associated with frequency of accompanying NME on MR and positive pathologic result, clinicopathologic features were compared between breast cancers with NME and without NME, and between breast cancers with positive NME and negative NME using the Student t-test or Chi-square test. RESULTS: Of the 163 invasive breast cancers, 123(75.5%) cancers presented as only mass feature and 40(24.5%) cancers had accompanying NME around the index mass. Of the 40 accompanying NME, 22 (55%) had positive pathologic results and 18 (45%) had negative results. The HER2 positive status was significantly associated with positive pathologic results of accompanying NME (P = .016). CONCLUSION: Accompanying NME on preoperative MR imaging showed malignant pathologic results in 55%. The HER2 positive IDC was more frequently accompanied by malignant NME.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherPublic Library of Science-
dc.relation.isPartOfPLOS ONE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHBreast Neoplasms/diagnostic imaging*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMagnetic Resonance Imaging/methods*-
dc.subject.MESHMiddle Aged-
dc.titleThe clinical significance of accompanying NME on preoperative MR imaging in breast cancer patient-
dc.typeArticle-
dc.publisher.locationUnited States-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Radiology-
dc.contributor.googleauthorHye Mi Gweon-
dc.contributor.googleauthorJoon Jeong-
dc.contributor.googleauthorEun Ju Son-
dc.contributor.googleauthorJi Hyun Youk-
dc.contributor.googleauthorJeong-Ah Kim-
dc.contributor.googleauthorKyung Hee Ko-
dc.identifier.doi10.1371/journal.pone.0178445-
dc.contributor.localIdA00888-
dc.contributor.localIdA01988-
dc.contributor.localIdA02537-
dc.contributor.localIdA03727-
dc.contributor.localIdA00265-
dc.relation.journalcodeJ02540-
dc.identifier.eissn1932-6203-
dc.identifier.pmid28558007-
dc.contributor.alternativeNameGweon, Hye Mi-
dc.contributor.alternativeNameKim, Jeong Ah-
dc.contributor.alternativeNameSon, Eun Ju-
dc.contributor.alternativeNameYouk, Ji Hyun-
dc.contributor.alternativeNameJeong, Joon-
dc.contributor.affiliatedAuthorKim, Jeong Ah-
dc.contributor.affiliatedAuthorSon, Eun Ju-
dc.contributor.affiliatedAuthorYouk, Ji Hyun-
dc.contributor.affiliatedAuthorJeong, Joon-
dc.contributor.affiliatedAuthorGweon, Hye Mi-
dc.citation.titlePLoS One-
dc.citation.volume12-
dc.citation.number5-
dc.citation.startPagee0178445-
dc.identifier.bibliographicCitationPLOS ONE, Vol.12(5) : e0178445, 2017-
dc.date.modified2017-11-01-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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