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횡문근융해증의 이해

Other Titles
 Rhabdomyolysis 
Authors
 이정환  ;  최영철 
Citation
 Korean Journal of Neuromuscular Disorders (대한신경근육질환학회지), Vol.8(1) : 22-27, 2016 
Journal Title
 Korean Journal of Neuromuscular Disorders (대한신경근육질환학회지) 
ISSN
 2093-3312 
Issue Date
2016
Keywords
Rhabdomyolysis ; Myopathy ; Differential diagnosis ; Acute kidney injury
Abstract
Rhabdomyolysis is commonly defined as elevation of serum creatine kinase (sCK) level of above 10 times the upper limit of normal followed by a rapid decrease to normal values. Typical clinical features are myalgia, muscular weakness and black colored urine and the most common complication is acute renal failure due to acute tubular necrosis as a result of mechanical obstruction by myoglobin. Most patients experience one episode of rhabdomyolysis by substance abuse, medication, trauma, or seizures. When patients have a history of recurrent rhabdomyolysis, exercise intolerance or family members with neuromuscular disorders, further evaluations for genetic neuromuscular disorder are required. Mortality rate of rhabdomyolysis is, generally, below 10%, but very high in patients with acute renal failure. So, the management in the acute phase should be performed with maintenance of renal function and restore of metabolic derangements by various conservative managements, such as volume replacement.
Files in This Item:
T201606320.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Jung Hwan(이정환)
Choi, Young Chul(최영철) ORCID logo https://orcid.org/0000-0001-5525-6861
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/153135
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