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체외 생명유지술을 이용한 중독 환자의 치료: 체계적 고찰

Other Titles
 Extracorporeal Life Support in Treatment of Poisoning Patient: Systematic Review 
 이용희  ;  고동률  ;  공태영  ;  주영선  ;  유제성  ;  정성필 
 Journal of the Korean Society of Clinical Toxicology (대한임상독성학회지), Vol.14(1) : 1-8, 2016 
Journal Title
Journal of the Korean Society of Clinical Toxicology(대한임상독성학회지)
Issue Date
Cardiopulmonary bypass ; Extracorporeal circulation ; Extracorporeal membrane oxygenation ; Poisoning
Purpose: Extracorporeal life support (ECLS) is a term used to describe a number of modalities including extracorporeal membrane oxygenation (ECMO) to support cardiac and/or pulmonary systems. The purpose of this study is
to review the available evidence regarding the effect of ECLS in patients with acute poisoning.

Methods: Electronic literature searches with PubMed, Embase, Cochrane library, and KoreaMed were conducted for identification of relevant studies addressing ECLS in treatment of acute poisoning. The literature search was
conducted by two investigators in March, 2016 with publication language restricted to English and Korean. The toxic substance, technique of ECLS, and final outcome of each case were analyzed.

Results: The final analysis included 64 articles including 55 case reports. There were no articles classified according to a high level of evidence such as randomized trial and prospective cohort study. ECLS treatment was used in
the management of patients poisoned with 36 unique substances. Venovenous ECMO was performed in 4 cases. Among the reported cases, 10 patients died despite treatment with ECLS.

Conclusion: Evidence supporting ECLS for patients with acute poisoning is inadequate. However, many case reports suggest that early consideration of ECLS in poisoned patients with refractory cardiac arrest or hemodynamic
compromise refractory to standard therapies may be beneficial.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Emergency Medicine (응급의학교실) > 1. Journal Papers
Yonsei Authors
Ko, Dong Ryul(고동률) ORCID logo https://orcid.org/0000-0002-3098-2784
Kong, Tae Young(공태영) ORCID logo https://orcid.org/0000-0002-4182-7245
You, Je Sung(유제성) ORCID logo https://orcid.org/0000-0002-2074-6745
Chung, Sung Phil(정성필) ORCID logo https://orcid.org/0000-0002-3074-011X
Joo, Young Seon(주영선)
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