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Association between the triglyceride to high-density lipoprotein cholesterol ratio and insulin resistance in Korean adolescents: a nationwide population-based study

Authors
 Jae-Min Park  ;  Jee-Yon Lee  ;  Jae June Dong  ;  Duk-Chul Lee  ;  Yong-Jae Lee 
Citation
 Journal of Pediatric Endocrinology & Metabolism, Vol.29(11) : 1259-1265, 2016 
Journal Title
 Journal of Pediatric Endocrinology & Metabolism 
ISSN
 0334-018X 
Issue Date
2016
Abstract
BACKGROUND: Studies have suggested the triglyceride to high-density lipoprotein cholesterol ratio (TG/HDL-C) as a surrogate marker of insulin resistance. However, few studies have examined the association between TG/HDL-C and insulin resistance in the general adolescent population. This study aimed to examine the association between TG/HDL-C and insulin resistance in a nationally representative sample of Korean adolescents. METHODS: A total of 2649 participants aged 12-18 years were selected from the 2007 to 2010 Korean National Health and Nutrition Examination Survey (KNHANES). Insulin resistance was defined as the homeostatic model assessment of insulin resistance (HOMA-IR) values greater than the 80th percentile. RESULTS: The mean values of most cardiometabolic variables increased proportionally with TG/HDL-C quartiles. Compared to individuals in the lowest TG/HDL-C quartile, the odds ratio for insulin resistance for individuals in the highest quartile was 2.91 in boys and 2.38 in girls after adjusting for confounding variables. CONCLUSIONS: This study suggests that TG/HDL-C could be a convenient marker for identifying Korean adolescents with insulin resistance.
Full Text
https://www.degruyter.com/view/j/jpem.2016.29.issue-11/jpem-2016-0244/jpem-2016-0244.xml
DOI
10.1515/jpem-2016-0244
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실) > 1. Journal Papers
Yonsei Authors
동재준(Dong, Jae June) ORCID logo https://orcid.org/0000-0002-2420-2155
박재민(Park, Jae Min) ORCID logo https://orcid.org/0000-0001-8873-8832
이덕철(Lee, Duk Chul) ORCID logo https://orcid.org/0000-0001-9166-1813
이용제(Lee, Yong Jae) ORCID logo https://orcid.org/0000-0002-6697-476X
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/152631
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