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췌장암 환자에서 검출된 항-f(ce) 항체 증례보고

Other Titles
 A Case Report of Anti-f(ce) Identified in a Patient with Pancreatic Cancer 
Authors
 나현진  ;  신새암  ;  김신영  ;  이은경  ;  김현옥 
Citation
 Korean Journal of Blood Transfusion (대한수혈학회지), Vol.27(2) : 174-182, 2016 
Journal Title
 Korean Journal of Blood Transfusion (대한수혈학회지) 
ISSN
 1226-9336 
Issue Date
2016
Keywords
Rh compound antigens ; Anti-f(ce) ; Unexpected antibody identification
Abstract
Anti-f(ce) is a rare unexpected antibody against the ce(f) antigen. The aim of this study is to report a second case of anti-f(ce) identified in a patient. A 66-year-old-male with pancreatic cancer received percutaneous transhepatic biliary drainage. During pretransfusion tests, anti-f(ce) was identified. He had a history of multiple transfusions and was transfused with 2 units of antiglobulin crossmatch compatible RBCs without any adverse reactions. To confirm that the antibody was specific for ce(f) antigen, we crossmatched the patient’s serum with RhD-positive red cells of Rh phenotype DcE, DCcEe, DCce, and DCe; all results were negative. Conversely, a crossmatch with RhD-negative red cells of Rh phenotype ce, Cce, and cEe, showed positive results for Rh phenotype ce and cEe red cells. Among the four reports that confirmed anti-e, we discovered the possibility of co-existence of anti-C or misidentification of anti-Ce as anti-e. Therefore, when antibodies against Rh antigens are identified, the possibility of co-existence of antibodies against compound antigens should be considered. Using unexpected antibody identification panel that ce(f) antigen positive red cells are marked is recommended for sensitive detection of anti-f(ce).
Files in This Item:
T201604404.pdf Download
DOI
10.17945/kjbt.2016.27.2.174
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Sin Young(김신영) ORCID logo https://orcid.org/0000-0002-2609-8945
Kim, Hyun Ok(김현옥) ORCID logo https://orcid.org/0000-0002-4964-1963
Nah, Hyunjin(나현진)
Lee, Eunkyung(이은경)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/152503
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