Adult ; Aged ; Antitubercular Agents/therapeutic use* ; Chi-Square Distribution ; Educational Status ; Employment ; Female ; Health Promotion ; Housing ; Humans ; Logistic Models ; Male ; Medication Adherence* ; Middle Aged ; Odds Ratio ; Prospective Studies ; Republic of Korea ; Risk Factors ; Social Conditions* ; Treatment Outcome ; Tuberculosis, Pulmonary/diagnosis ; Tuberculosis, Pulmonary/drug therapy* ; Tuberculosis, Pulmonary/psychology ; Young Adult
Abstract
SETTING: Tuberculosis (TB) remains one of the main concerns in global health. One of the main threats to treatment success is patient non-adherence to anti-tuberculosis treatment.
OBJECTIVE: To identify the relation between social conditions and treatment adherence in a prospective cohort setting in an intermediate TB burden country.
DESIGN: To identify associations between poor adherence and social conditions, including educational level, type of residence and occupation, we constructed hierarchical logistic regression models.
RESULTS: A total of 551 participants were included in the study. Low educational levels, poor housing and occupations in the construction and manufacturing industries and service sectors were associated with poor adherence; this association was likely to be differentiated by previous history of anti-tuberculosis treatment.
CONCLUSION: Policy making should focus on improving the social conditions of patients by working towards better housing conditions and providing health promoting working conditions to enable treatment adherence.