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Optimized Performance of FlightPlan during Chemoembolization for Hepatocellular Carcinoma: Importance of the Proportion of Segmented Tumor Area

DC FieldValueLanguage
dc.contributor.author김용표-
dc.contributor.author염태준-
dc.contributor.author은나래-
dc.contributor.author이광훈-
dc.contributor.author주승문-
dc.date.accessioned2017-10-26T07:23:51Z-
dc.date.available2017-10-26T07:23:51Z-
dc.date.issued2016-
dc.identifier.issn1229-6929-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/151974-
dc.description.abstractOBJECTIVE: To evaluate retrospectively the clinical effectiveness of FlightPlan for Liver (FPFL), an automated tumor-feeding artery detection software in cone-beam CT angiography (CBCTA), in identifying tumor-feeding arteries for the treatment of hepatocellular carcinoma (HCC) using three different segmentation sensitivities. MATERIALS AND METHODS: The study included 50 patients with 80 HCC nodules who received transarterial chemoembolization. Standard digital subtracted angiography (DSA) and CBCTA were systematically performed and analyzed. Three settings of the FPFL software for vascular tree segmentation were tested for each tumor: the default, Group D; adjusting the proportion of segmented tumor area between 30 to 50%, Group L; and between 50 to 80%, Group H. RESULTS: In total, 109 feeder vessels supplying 80 HCC nodules were identified. The negative predictive value of DSA, FPFL in groups D, L, and H was 56.8%, 87.7%, 94.2%, 98.5%, respectively. The accuracy of DSA, FPFL in groups D, L, and H was 62.6%, 86.8%, 93.4%, 95.6%, respectively. The sensitivity, negative predictive value (NPV), and accuracy of FPFL were higher in Group H than in Group D (p = 0.041, 0.034, 0.005). All three segmentation sensitivity groups showed higher specificity, positive predictive value, NPV, and accuracy of FPFL, as compared to DSA. CONCLUSION: FlightPlan for Liver is a valuable tool for increasing detection of HCC tumor feeding vessels, as compared to standard DSA analysis, particularly in small HCC. Manual adjustment of segmentation sensitivity improves the accuracy of FPFL.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherKorean Society of Radiology-
dc.relation.isPartOfKOREAN JOURNAL OF RADIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAngiography, Digital Subtraction/methods-
dc.subject.MESHCarcinoma, Hepatocellular/blood supply-
dc.subject.MESHCarcinoma, Hepatocellular/diagnostic imaging-
dc.subject.MESHCarcinoma, Hepatocellular/pathology-
dc.subject.MESHCarcinoma, Hepatocellular/therapy*-
dc.subject.MESHChemoembolization, Therapeutic/methods*-
dc.subject.MESHCone-Beam Computed Tomography/methods-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHLiver Neoplasms/blood supply-
dc.subject.MESHLiver Neoplasms/diagnostic imaging-
dc.subject.MESHLiver Neoplasms/pathology-
dc.subject.MESHLiver Neoplasms/therapy*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeovascularization, Pathologic/diagnostic imaging-
dc.subject.MESHNeovascularization, Pathologic/therapy-
dc.subject.MESHPredictive Value of Tests-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHSensitivity and Specificity-
dc.subject.MESHSoftware-
dc.titleOptimized Performance of FlightPlan during Chemoembolization for Hepatocellular Carcinoma: Importance of the Proportion of Segmented Tumor Area-
dc.typeArticle-
dc.publisher.locationKorea (South)-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Radiology-
dc.contributor.googleauthorSeung-Moon Joo-
dc.contributor.googleauthorYong Pyo Kim-
dc.contributor.googleauthorTae Jun Yum-
dc.contributor.googleauthorNa Lae Eun-
dc.contributor.googleauthorDahye Lee-
dc.contributor.googleauthorKwang-Hun Lee-
dc.identifier.doi10.3348/kjr.2016.17.5.771-
dc.contributor.localIdA04975-
dc.contributor.localIdA04778-
dc.contributor.localIdA02676-
dc.contributor.localIdA05043-
dc.contributor.localIdA00754-
dc.relation.journalcodeJ02884-
dc.identifier.eissn2005-8330-
dc.identifier.pmid27587967-
dc.subject.keywordChemoembolization-
dc.subject.keywordCone-beam CT-
dc.subject.keywordFlightPlan-
dc.subject.keywordHCC-
dc.subject.keywordHepatoma-
dc.subject.keywordLiver-
dc.subject.keywordTACE-
dc.contributor.alternativeNameKim, Yong Pyo-
dc.contributor.alternativeNameYum, Tae Jun-
dc.contributor.alternativeNameEun, Na Lae-
dc.contributor.alternativeNameLee, Kwang Hun-
dc.contributor.alternativeNameJoo, Seung Moon-
dc.contributor.affiliatedAuthorYum, Tae Jun-
dc.contributor.affiliatedAuthorEun, Na Lae-
dc.contributor.affiliatedAuthorLee, Kwang Hun-
dc.contributor.affiliatedAuthorJoo, Seung Moon-
dc.contributor.affiliatedAuthorKim, Yong Pyo-
dc.citation.volume17-
dc.citation.number5-
dc.citation.startPage771-
dc.citation.endPage778-
dc.identifier.bibliographicCitationKOREAN JOURNAL OF RADIOLOGY, Vol.17(5) : 771-778, 2016-
dc.date.modified2017-10-24-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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