Cited 8 times in
Dynamic contrast-enhanced MRI coupled with a subtraction technique is useful for treatment response evaluation of malignant melanoma hepatic metastasis
DC Field | Value | Language |
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dc.contributor.author | 김명진 | - |
dc.contributor.author | 이민수 | - |
dc.contributor.author | 임준석 | - |
dc.contributor.author | 김한솔 | - |
dc.contributor.author | 박미숙 | - |
dc.contributor.author | 백송이 | - |
dc.date.accessioned | 2017-10-26T07:11:51Z | - |
dc.date.available | 2017-10-26T07:11:51Z | - |
dc.date.issued | 2016 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/151727 | - |
dc.description.abstract | PURPOSE: To determine whether contrast-enhanced MRI including subtraction sequences can predict the treatment response of melanoma liver metastasis. RESULTS: High precontrast T1 signal intensity (SI) of melanoma lesions obscured detection of enhancement after contrast injection. It was impossible to determine whether or not enhancement occurred in the majority of lesions (85.4%, n = 35/41) without including the subtraction technique. Positive enhancement was identified in 14.6% (n = 6/41) of patients without subtraction images, but increased to 68.3% (n = 28/41) by including subtraction images. Follow-up studies determined lesion progression in 34.1% (n = 14/41) of patients. Positive enhancement on the subtraction image (odds ratio = 12.1, P = 0.048) and intermediate high T2 SI (odds ratio = 8.16, P = 0.040) were significantly associated with higher risk of lesion progression. MATERIALS AND METHODS: Patients who underwent MRI for melanoma liver metastases between January 2007 and February 2015 were enrolled. The study analyzed 41 liver metastases in 15 patients [11 male and four female; median age 56 years (range 21-81)] for size, lesion enhancement with and without subtraction images, and T2 SI. Follow-up imaging studies were used to determine treatment response. Data were analyzed with generalized estimating equations. CONCLUSIONS: MRI including the subtraction technique is useful for determining the treatment response of melanoma liver metastases. Lesion contrast enhancement and intermediate high T2 SI increased the risk of lesion progression. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Impact Journals | - |
dc.relation.isPartOf | ONCOTARGET | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Contrast Media/therapeutic use* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Liver Neoplasms/diagnostic imaging* | - |
dc.subject.MESH | Liver Neoplasms/pathology | - |
dc.subject.MESH | Liver Neoplasms/secondary* | - |
dc.subject.MESH | Magnetic Resonance Imaging/methods* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Melanoma/diagnostic imaging* | - |
dc.subject.MESH | Melanoma/pathology | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Metastasis | - |
dc.subject.MESH | Young Adult | - |
dc.title | Dynamic contrast-enhanced MRI coupled with a subtraction technique is useful for treatment response evaluation of malignant melanoma hepatic metastasis | - |
dc.type | Article | - |
dc.publisher.location | United States | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Radiology | - |
dc.contributor.googleauthor | Minsu Lee | - |
dc.contributor.googleauthor | Song-Ee Baek | - |
dc.contributor.googleauthor | Jieun Moon | - |
dc.contributor.googleauthor | Yun Ho Roh | - |
dc.contributor.googleauthor | Joon Seok Lim | - |
dc.contributor.googleauthor | Mi-Suk Park | - |
dc.contributor.googleauthor | Myeong-Jin Kim | - |
dc.contributor.googleauthor | Honsoul Kim | - |
dc.identifier.doi | 10.18632/oncotarget.9567 | - |
dc.contributor.localId | A04624 | - |
dc.contributor.localId | A03408 | - |
dc.contributor.localId | A01099 | - |
dc.contributor.localId | A01463 | - |
dc.contributor.localId | A01822 | - |
dc.contributor.localId | A00426 | - |
dc.relation.journalcode | J02421 | - |
dc.identifier.eissn | 1949-2553 | - |
dc.identifier.pmid | 27229529 | - |
dc.subject.keyword | mRECIST | - |
dc.subject.keyword | magnetic resonance imaging | - |
dc.subject.keyword | melanoma liver metastasis | - |
dc.subject.keyword | subtraction technique | - |
dc.subject.keyword | treatment response | - |
dc.contributor.alternativeName | Kim, Myeong Jin | - |
dc.contributor.alternativeName | Lee, Minsu | - |
dc.contributor.alternativeName | Lim, Joon Seok | - |
dc.contributor.alternativeName | Kim, Hon Soul | - |
dc.contributor.alternativeName | Park, Mi Sook | - |
dc.contributor.alternativeName | Baek, Song Ee | - |
dc.contributor.affiliatedAuthor | Lee, Minsu | - |
dc.contributor.affiliatedAuthor | Lim, Joon Seok | - |
dc.contributor.affiliatedAuthor | Kim, Hon Soul | - |
dc.contributor.affiliatedAuthor | Park, Mi-Suk | - |
dc.contributor.affiliatedAuthor | Baek, Song Ee | - |
dc.contributor.affiliatedAuthor | Kim, Myeong Jin | - |
dc.citation.volume | 7 | - |
dc.citation.number | 25 | - |
dc.citation.startPage | 38513 | - |
dc.citation.endPage | 38522 | - |
dc.identifier.bibliographicCitation | ONCOTARGET, Vol.7(25) : 38513-38522, 2016 | - |
dc.date.modified | 2017-10-24 | - |
dc.identifier.rimsid | 45740 | - |
dc.type.rims | ART | - |
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