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Effect of cetrorelix acetate on apoptosis and apoptosis regulatory factors in cultured uterine leiomyoma cells

Authors
 Ja-Young Kwon  ;  Ki-Hyun Park  ;  Young-Nyun Park  ;  Nam-Hoon Cho 
Citation
 FERTILITY AND STERILITY, Vol.84(5) : 1526-1528, 2005 
Journal Title
FERTILITY AND STERILITY
ISSN
 0015-0282 
Issue Date
2005
MeSH
Adult ; Apoptosis/drug effects* ; Apoptosis/physiology ; Female ; Gonadotropin-Releasing Hormone/analogs & derivatives* ; Gonadotropin-Releasing Hormone/pharmacology ; Humans ; Leiomyoma/metabolism* ; Leiomyoma/pathology* ; Tumor Cells, Cultured ; Uterus/drug effects* ; Uterus/metabolism ; Uterus/pathology*
Keywords
16275262
Abstract
This report suggests the possibility that a gonadotropin-releasing hormone (GnRH) antagonist initiates apoptosis not only by causing a sex hormone deficit by inhibiting GnRH secretion in the pituitary gland, but also by acting directly on leiomyoma cells promoting apoptosis.
Full Text
http://www.sciencedirect.com/science/article/pii/S0015028205028219
DOI
10.1016/j.fertnstert.2005.06.022
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
Yonsei Authors
Kwon, Ja Young(권자영) ORCID logo https://orcid.org/0000-0003-3009-6325
Park, Ki Hyun(박기현)
Park, Young Nyun(박영년) ORCID logo https://orcid.org/0000-0003-0357-7967
Cho, Nam Hoon(조남훈) ORCID logo https://orcid.org/0000-0002-0045-6441
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/151503
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