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파상풍 항체 역가가 낮은 한국 성인에서 파상풍 변성독소 일회 주사의 효과

Other Titles
 Effect of a Single Tetanus Toxoid in Korean Adults with Low Tetanus Antibody Titers 
Authors
 노현웅  ;  김승호  ;  장문준  ;  심호식 
Citation
 Journal of the Korean Society of Emergency Medicine (대한응급의학회지), Vol.16(5) : 555-561, 2005 
Journal Title
 Journal of the Korean Society of Emergency Medicine (대한응급의학회지) 
ISSN
 1226-4334 
Issue Date
2005
MeSH
Tetanus ; Tetanus toxoid ; Immunization
Keywords
Tetanus ; Tetanus toxoid ; Immunization
Abstract
Purpose: The determination of tetanus prophylaxis according to patients’ memories of past immunization is inaccurate. However, by using the Tetanos Quick StickⓇ test, it is possible to select Korean adults with low tetanus antibody titers and to perform tetanus prophylaxis in the emergency department. In 1996, Ha reported that tetanus toxoid injection into healthy Korean adults revealed significant differences between the tetanus antibody titers at the beginning and the tetanus antibody titers after 1 week. Our purpose is to determine the effect of a single tetanus toxoid in Korean adults with low tetanus antibody titers. Methods: Blood samples were taken from 44 volunteers for a period of 6 weeks. All samples were analyzed using the Tetanus IgG ELISA (enzyme-linked immunosorbent assay) method. Results: The results for tetanus antibody titers at the beginning and after 1 week, 2 weeks, 4 weeks, and 6 weeks were 0.04+/-0.05 IU/mL, 1.22+/-3.63 IU/mL, 4.99+/-7.3 6 IU/mL, 8.36+/-11.10 IU/mL and 6.59+/-9.21 IU/mL respectively. There was a statistically significant defference between the tetanus antibody titers at the beginning and the tetanus antibody titers after 2 weeks. There was no statistically significant defference between the tetanus antibody titers after 2 weeks and 6 weeks. After 4 weeks, all subjects’ tetanus antibody titers were at the protective level. Conclusion: A single tetanus toxoid injection is effective in Korean adults with low tetanus antibody titers.
Files in This Item:
T200501248.pdf Download
DOI
OAK-2005-05823
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Emergency Medicine (응급의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Medical Education (의학교육학과) > 1. Journal Papers
Yonsei Authors
Kim, Seung Ho(김승호)
Shim, Ho Shik(심호식)
Yoon, Yoo Sang(윤유상)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/151322
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