0 165

Cited 45 times in

Mortality risk factors of Acinetobacter baumannii bacteraemia

 J. Y. Choi  ;  Y. S. Park  ;  C. O. Kim  ;  Y. S. Park  ;  H. J. Yoon  ;  S. Y. Shin  ;  Y.-A. Kim  ;  Y. G. Song  ;  D. Yong  ;  K. Lee  ;  J. M. Kim 
 INTERNAL MEDICINE JOURNAL, Vol.35(10) : 599-603, 2005 
Journal Title
Issue Date
Acinetobacter Infections/drug therapy ; Acinetobacter Infections/microbiology ; Acinetobacter Infections/mortality* ; Acinetobacter baumannii/isolation & purification* ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Bacteremia/drug therapy ; Bacteremia/microbiology ; Bacteremia/mortality* ; Child ; Child, Preschool ; Cohort Studies ; Drug Resistance, Bacterial ; Female ; Humans ; Infant ; Korea/epidemiology ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors ; Survival Rate
Acinetobacter ; bacteraemia ; mortality ; risk factors
BACKGROUND: Acinetobacter baumannii is one of the most important nosocomial pathogens, and its multiple antibiotic resistance has emerged as an obstacle in the treatment of these infections worldwide. AIMS: To identify risk factors of mortality for A. baumannii bacteraemia. METHODS: A retrospective cohort study of 72 patients with significant A. baumannii bacteraemia was conducted to evaluate risk factors for mortality. RESULTS: The median age of the 72 enrolled patients was 48 years, 96% of the cases were hospital-acquired, and the bacteraemia-related mortality rate was 29% (21 of 72 patients). Univariate analysis revealed that the risk factors for mortality included: an elevated acute physiology and chronic health evaluation (APACHE II) score, receipt of in vitro ineffective definitive antimicrobial therapy, in vitro A. baumannii resistance to cefoperazone/ sulbactam, neutropenia, and presentation with septic shock. Multivariate analysis reveals that the independent risk factors for mortality are neutropenia and elevated APACHE II scores. CONCLUSION: Risk factors such as neutropenia and elevated APACHE II scores are found to be associated with higher mortality rates of A. baumannii bacteraemia. Further study is necessary for the determination of optimal strategies for both the prevention and treatment of these infections.
Full Text
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Yeon A(김연아)
Kim, June Myung(김준명)
Kim, Chang Oh(김창오) ORCID logo https://orcid.org/0000-0002-0773-5443
Park, Yoon Seon(박윤선)
Park, Yoon Soo(박윤수)
Song, Young Goo(송영구) ORCID logo https://orcid.org/0000-0002-0733-4156
Shin, So Youn(신소연)
Yong, Dong Eun(용동은) ORCID logo https://orcid.org/0000-0002-1225-8477
Yoon, Hee Jung(윤희정)
Lee, Kyungwon(이경원) ORCID logo https://orcid.org/0000-0003-3788-2134
Choi, Jun Yong(최준용) ORCID logo https://orcid.org/0000-0002-2775-3315
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.