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경구용 steroid나 danazol로 성공적으로 치료된 후천성혈우병 A 2예

Other Titles
 Two Cases of Acquired Hemophilia A Successfully Treated with Oral Steroid or Danazol 
Authors
 박선영  ;  김진석  ;  김유리  ;  박인혜  ;  정준원  ;  이승태  ;  한지숙  ;  민유홍 
Citation
 Korean Journal of Hematology, Vol.40(1) : 58-63, 2005 
Journal Title
 Korean Journal of Hematology 
ISSN
 1738-7949 
Issue Date
2005
MeSH
Acquired hemophilia A ; Factor VIII inhibitor ; Immunosuppressive therapy
Keywords
Acquired hemophilia A ; Factor VIII inhibitor ; Immunosuppressive therapy
Abstract
Acquired Hemophilia A is a rare and considerably life-threatening coagulopathy, which is caused by the development of autoantibodies against factor VIII (FVIII) in non-hemophilic adults. Acquired FVIII inhibitors can be associated with diverse conditions, such as malignant disorders, medications, autoimmune diseases, postpartum states and others. These autoantibodies inhibit normal coagulation, had results in bleeding complications, which can contribute to mortality in a high percentages of cases. Effective control of the disorder can be achieved by prompt diagnosis and appropriate managements. Generally, the managements of acquired hemophilia A are aimed at treating the acute bleeding and eliminating inhibitors by immunosuppression. Although a range of treatment options exists for patients with acquired hemophilia A, there is no consensus with regard to the optimal therapies for this disorder. Herein, two cases, an 82-year-old man and a 78-year-old man who were successfully treated by steroid or danazol, which is a relatively mild immunosuppressive agent, are reported.
Files in This Item:
T200500976.pdf Download
DOI
10.5045/kjh.2005.40.1.58
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Yu Ri(김유리) ORCID logo https://orcid.org/0000-0001-5505-0142
Kim, Jin Seok(김진석) ORCID logo https://orcid.org/0000-0001-8986-8436
Min, Yoo Hong(민유홍) ORCID logo https://orcid.org/0000-0001-8542-9583
Park, Sun Young(박선영)
Park, In Hae(박인혜)
Lee, Seung Tae(이승태)
Cheong, June-Won(정준원) ORCID logo https://orcid.org/0000-0002-1744-0921
Hahn, Jee Sook(한지숙)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/151152
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