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투석을 시작한 말기 신부전증 환자에서의 좌심실 이완 기능과 예비능

Other Titles
 Left Ventricular Longitudinal Diastolic Function and Functional Reserve in ESRD Patients Starting Dialysis Treatment 
Authors
 류동열  ;  강신욱  ;  박성하  ;  유태현  ;  김형종  ;  최훈영  ;  김주성  ;  강석민  ;  임세중  ;  정남식  ;  하종원 
Citation
 Korean Journal of Nephrology (대한신장학회지), Vol.24(1) : 100-107, 2005 
Journal Title
 Korean Journal of Nephrology (대한신장학회지) 
ISSN
 1225-0015 
Issue Date
2005
MeSH
Diastolic function ; Diastolic functional reserve ; Doppler tissue imaging ; End stage renal disease (ESRD)
Keywords
Diastolic function ; Diastolic functional reserve ; Doppler tissue imaging ; End stage renal disease (ESRD)
Abstract
BACKGROUND: Abnormalities of the left ventricular (LV) diastolic dysfunction are common in patients with end-stage renal disease (ESRD). Recently, Doppler tissue imaging (DTI) has been introduced as a method to evaluate diastolic function or myocardial relaxation by measuring mitral annulus velocity during diastole. This study was undertaken to assess resting diastolic function and diastolic functional reserve during exercise in ESRD patients starting dialysis treatment. METHODS: Mitral inflow velocities by Doppler echocardiography and septal mitral annular velocities by DTI were measured at rest and during supine bicycle exercise in 22 new ESRD patients and 23 age- and sex-matched subjects with normal renal function as a control. RESULTS: LV end-diastolic and end-systolic dimensions, septal thickness, and left atrial volume index were significantly higher in patients with ESRD compared with those of controls (p<0.01). LV ejection fraction was significantly lower in ESRD group (p<0.05). There were no significant differences in mitral inflow velocities (E, E/A, DT) between the two groups except A velocity, which was significantly higher in ESRD group (p<0.01). However, early diastolic mitral annular velocity (E’) at rest (5.3±1.3 cm/sec vs. 6.5±1.5 cm/sec, p=0.013) and augmentation of E’ with exercise (?E’) were significantly lower in ESRD group compared with controls (at 25W exercise, 1.3±1.6 cm/sec vs. 4.0±3.0 cm/sec, p=0.002; at 50W exercise, 3.3±2.3 cm/sec vs. 6.5±5.3 cm/sec, p=0.030). CONCLUSION: Unlike conventional mitral inflow parameters, longitudinal resting diastolic function and diastolic functional reserve during exercise assessed by DTI were significantly reduced in ESRD patients starting dialysis treatment.
Files in This Item:
T200500829.pdf Download
DOI
OAK-2005-04488
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Seok Min(강석민) ORCID logo https://orcid.org/0000-0001-9856-9227
Kang, Shin Wook(강신욱) ORCID logo https://orcid.org/0000-0002-5677-4756
Kim, Joo Sung(김주성)
Kim, Hyung Jong(김형종)
Ryu, Dong Ryeol(류동열)
Park, Sung Ha(박성하) ORCID logo https://orcid.org/0000-0001-5362-478X
Yoo, Tae Hyun(유태현) ORCID logo https://orcid.org/0000-0002-9183-4507
Rim, Se Joong(임세중) ORCID logo https://orcid.org/0000-0002-7631-5581
Chung, Nam Sik(정남식)
Choi, Hoon Young(최훈영) ORCID logo https://orcid.org/0000-0002-4245-0339
Ha, Jong Won(하종원) ORCID logo https://orcid.org/0000-0002-8260-2958
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/151086
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