147 463

Cited 49 times in

Prealbumin is Not Sensitive Indicator of Nutrition and Prognosis in Critical Ill Patients

Authors
 Seung Hui Lim  ;  Jong Seok Lee  ;  Sang Hee Chae  ;  Bo Sook Ahn  ;  Dong Jin Chang  ;  Cheung Soo Shin 
Citation
 YONSEI MEDICAL JOURNAL, Vol.46(1) : 21-26, 2005 
Journal Title
YONSEI MEDICAL JOURNAL
ISSN
 0513-5796 
Issue Date
2005
MeSH
Aged ; Aged, 80 and over ; Biomarkers ; Critical Illness* ; Female ; Humans ; Male ; Malnutrition/blood* ; Malnutrition/diagnosis* ; Middle Aged ; Nutrition Assessment* ; Prealbumin/metabolism* ; Prognosis ; Sensitivity and Specificity
Keywords
Critical ill patients ; prealbumin ; prognostic indicator
Abstract
It was reported that 30-50% of inpatients are in a malnutrition status. Measuring the prealbumin level is a sensitive and cost-effective method for assessing the severity of illness in critically or chronically ill patients. However it is uncertain whether or not the prealbumin level correlates with the level of nutrition support and outcomes in critically ill patients. The aim of this study was to evaluate serum prealbumin level as an indicator of the effectiveness of nutrition support and the prognosis in critically ill patients. Forty-four patients who received total parenteral nutrition for more than 7 days at an intensive care unit (ICU) were studied. The serum prealbumin was measured at the initial time of nutrition support and at the almost seventh day since the first measurement. The patients were allocated into two groups. In Group 1 (n=31) and 2 (n=13), the prealbumin level increased and decreased, respectively. Age, APACHE II score, nutrition status, nutritional requirement and amount of supply, mortality, hospital day and ICU day in the two groups were compared. The serum prealbumin level increased in 31 out of the 44 patients. The average calorie intake was 1334 Kcal/day (83% of energy requirement) in Group 1 and 1170 kcal/day (76% of energy requirement) in Group 2 (p=0.131). The mortality was 42% in Group 1 and 54% in Group 2 (p=0.673). The average hospital day/ ICU day in Groups 1 and 2 were 80 days/38 days and 60 days/31 days respectively. In conclusion, in critically ill patients, the serum prealbumin level did not respond sensitively to nutritional support. In addition an increase in the prealbumin level dose not indicate a better prognosis for critically ill patients.
Files in This Item:
T200500754.pdf Download
DOI
10.3349/ymj.2005.46.1.21
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
Yonsei Authors
Shin, Cheung Soo(신증수) ORCID logo https://orcid.org/0000-0001-7829-8458
Lee, Jong Seok(이종석) ORCID logo https://orcid.org/0000-0002-7945-2530
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/151042
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links