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다낭성 난소 증후군 환자에서 Isoflavone 섭취에 따른 혈중 생화학적 지표의 변화

Other Titles
 The Effect of Isoflavone Supplementation on Plasma Biochemical Parameters of Women with Polycystic Ovary Syndrome 
Authors
 원형재  ;  강주희  ;  이민준  ;  윤선  ;  박기현  ;  조동제  ;  송찬호  ;  이병석 
Citation
 Korean Journal of Fertility and Sterility (대한불임학회지), Vol.32(1) : 9-16, 2005 
Journal Title
 Korean Journal of Fertility and Sterility (대한불임학회지) 
ISSN
 1226-2951 
Issue Date
2005
MeSH
Isoflavone ; Polycystic ovary syndrome ; Hormone levels ; Lipid profiles ; Total antioxidant status
Keywords
Isoflavone ; Polycystic ovary syndrome ; Hormone levels ; Lipid profiles ; Total antioxidant status
Abstract
OBJECTIVE: This study was performed to evaluate the effect of isoflavone supplementation on hormone levels, lipid profiles and total antioxidant status in patients with polycystic ovary syndrome. METHODS: Total 11 women with polycystic ovary syndrome were supplemented daily with 150mg of isoflavone for 6 months. Blood samples were collected 0, 3, and 6 months after supplement of isoflavone for analysis of LH, FSH, E2, testosterone, free testosterone, SHBG levels, serum lipid profiles, and total antioxidant status (TAS). RESULTS: After 6 months isoflavone supplementation, the hormone levels did not change significantly. Serum lipid profiles did not show any significant change in total cholesterol, LDL-cholesterol, triglyceride, lipoprotein(a), and free fatty acid levels. However, there was significant increase in HDLcholesterol (p<0.05) for 3 months. Total antioxidant status was increased significantly after isoflavone supplementation for 6 months (p<0.05). CONCLUSION: Isoflavone supplementation showed positive effects on the HDL-cholesterol and total antioxidant status. it is implicated that isoflavone supplementation will may have a effect on cardiovascular disease in patients with polycystic ovary syndrome.
Files in This Item:
T200500692.pdf Download
DOI
OAK-2005-04101
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Park, Ki Hyun(박기현)
Song, Chan Ho(송찬호)
Won, Hyung Jae(원형재)
Lee, Byung Seok(이병석) ORCID logo https://orcid.org/0000-0001-6001-2079
Cho, Dong Je(조동제)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/150956
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