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척수손상 환자에서 혈청 cystatin C를 이용한 신기능 평가

Other Titles
 Serum Cystatin C for the Evaluation of Renal Function in the Spinal Cord Injured Patients 
Authors
 신지철  ;  박창일  ;  송원우  ;  김은주  ;  김상현  ;  이진우 
Citation
 Journal of the Korean Academy of Rehabilitation Medicine (대한재활의학회지), Vol.29(4) : 371-376, 2005 
Journal Title
 Journal of the Korean Academy of Rehabilitation Medicine (대한재활의학회지) 
ISSN
 1225-584X 
Issue Date
2005
MeSH
Cystatin C ; Creatinine clearance ; Renal function ; Spinal cord injury
Keywords
Cystatin C ; Creatinine clearance ; Renal function ; Spinal cord injury
Abstract
Objective: To evaluate the renal function by investigating the relationship among serum cystatin C, serum creatinine, creatinine clearance and the average of bilateral ERPF (effective renal plasma flow) ratio of the MAG3 renal scan for the spinal cord injured patients. Method: Seventy-one spinal cord injured patients who admitted to our department were evaluated from January 2004 to October 2004. Blood samples and 24-hour urine of all the subjects were collected for measuring serum cystatin C, serum creatinine and creatinine clearance. MAG3 renal scan was done for 47 subjects. Regression analysis and Pearson's correlation methods were utilized for statistical analysis. Results: There was significant correlation between 1/cystatin C and creatinine clearance (p<0.001) and the correlation coefficient between 1/cystatin C vs. creatinine clearance (R= 0.552) was bigger than that between 1/creatinine and creatinine clearance (R=0.329). The reciprocal of cystatin C was positively correlated with the average of bilateral ERPF ratio of MAG3 renal scan (p=0.01), while there was no significant correlation between 1/creatinine and the average of bilateral ERPF ratio. Conclusion: Measurement of serum cystatin C is a useful and convenient method for the evaluation of renal function in spinal cord injured patients.
Files in This Item:
T200500816.pdf Download
DOI
OAK-2005-04455
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Sang Hyun(김상현)
Kim, Eun Joo(김은주)
Park, Chang Il(박창일)
Shin, Ji Cheol(신지철) ORCID logo https://orcid.org/0000-0002-1133-1361
Lee, Jin Woo(이진우) ORCID logo https://orcid.org/0000-0002-0293-9017
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/150734
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