Cerebral angiography is an invasive technique and can induce various complications, such as neurologic complications. We describe two cases of retroperitoneal hematoma and renal injury, a rare complication of cerebral angiography. A 65-year-old male and 56-year-old male underwant cerebral angiography for stem cell implantation at a general hospital. The diagnoses of retroperitoneal hematoma and renal injury were delayed. On abdominal-pelvic CT, renal injury was demonstrated with a pseudoaneurysm and a retroperitoneal hematoma in the perirenal space. Interventional angiography was performed. Renal angiography showed that the contrast was extravasated with a pseudoaneurysm in the lower pole of right kidney. The feeding artery of the pseudoaneurysm was successfully embolized. Emergency physicians must consider a retroperitoneal hematoma and renal cortical injury after angiography, especially when patients present with hypotension and abdominal distention.