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아벨리노각막이상증으로 진단된 한국인 환자의 각막병변의 분류 및 임상양상

Other Titles
 The Classification and Clinical Characteristics in Korean Patients with Avellino Corneal Dystrophy 
 정소향  ;  김창염  ;  김응권 
 Journal of the Korean Ophthalmological Society (대한안과학회지), Vol.46(6) : 938-944, 2005 
Journal Title
 Journal of the Korean Ophthalmological Society (대한안과학회지) 
Issue Date
Purpose: To classify Avellino corneal dystrophy (ACD) into 3 groups by slit lamp photography and to evaluate the inter-group differences. Methods: DNA analysis was performed in one member from each of 45 families who were clinically diagnosed as ACD. Corneal opacities were classified into mild (group I), moderate (group II), and severe (group III) based on slit lamp photograph. Results: Six patients were confirmed as homozygous ACD and ninety-two as heterozygous ACD. One homozygous patient was revealed to have a novel phenotype. The age increased with increasing severity, and the proportion of females in group III was significantly higher than that of the other two groups (p=0.001). The prevalence of laser in situ keratomileusis (LASIK) increased in group III (p=0.001), and the incidence of pterygium increased in group I compared with the other two groups (p=0.025). Conclusions: ACD was aggravated with age, while pterygium and LASIK altered the natural course of ACD.
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1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Eung Kweon(김응권) ORCID logo https://orcid.org/0000-0002-1453-8042
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