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화학물질 우선순위 선정 기법(CRS-Korea)의 개발과 적용

Other Titles
 Development of Korean Chemical Ranking and Scoring System (CRS-Korea) and its Application to Prioritizing National Toxic Chemicals 
 박화성  ;  김예신  ;  이동수  ;  신용승  ;  최승필  ;  박성은  ;  김명현  ;  양지연  ;  신동천 
 Korean Journal of Environmental Toxicology, Vol.20(2) : 109-121, 2005 
Journal Title
Korean Journal of Environmental Toxicology(환경독성학회지)
Issue Date
chemical ranking and scoring system ; toxic chemicals ; priority ; risk
chemical ranking and scoring system ; toxic chemicals ; priority ; risk
A chemical ranking and scoring (CRS-Korea) system was developed and proposed to use as the first step to prioritize the toxic chemicals for the purpose of monitoring and detailed risk assessment that might follow as necessary. The CRS-Korea system takes a basic concept of risk assessment (both human health risk and ecological risk) in that risk score is determined by the product of toxicity score and exposure score. Included in the toxicity category are acute toxicity, chronic/sub -chronic toxicity, carcinogenicity, and other toxicity. The exposure category consists of quantity released to the environment, bioconcentration, and persistence. A consistent scheme and a comprehensive chemical data base are offered in the CRS-Korea system to calculate a score for the each component in the two categories by using specific physicochemical, fate, and toxic properties and the quantity of the chemical used. The toxicity score is obtained by adding up all the individual scores for the components in the toxicity category. The exposure score is determined by multiplication of the score of the quantity released with the sum of persistent score and bioconcentration score. Equal weight is given to the toxicity score and the exposure score. As the CRS-Korea system was applied to identify 50 national priority chemicals, it was found that significant data gap exists on toxicity and fate properties and that the uncertainty associated with estimating the quantify released to the environment is notably high. The proposed CRS system is only a screening tool in the first step toward the priority setting and should be used with expert judgement and other considerations necessary.
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Appears in Collections:
1. College of Medicine (의과대학) > Research Institute (부설연구소) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Preventive Medicine (예방의학교실) > 1. Journal Papers
Yonsei Authors
Shin, Dong Chun(신동천) ORCID logo https://orcid.org/0000-0003-4252-2280
Yang, Ji Yeon(양지연)
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