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Enhanced neurite outgrowth of rat neural cortical cells on surface-modified films of poly(lactic-co-glycolic acid)

DC Field Value Language
dc.contributor.author박봉주-
dc.contributor.author박종철-
dc.contributor.author한동욱-
dc.date.accessioned2017-05-04T07:33:25Z-
dc.date.available2017-05-04T07:33:25Z-
dc.date.issued2005-
dc.identifier.issn0141-5492-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/147453-
dc.description.abstractNeural cortical cells, isolated from prenatal rat cerebra, were grown on surface-modified poly(lactic-co-glycolic acid, 65:35) (PLGA) films coated with poly-D-lysine (PDL) with either laminin (LN), fibronectin (FN) or collagen (CN). Immunocytochemistry showed that the isolated cells were highly immunopositive for both neurofilament and MAP-2 with well-organized neurites and somatodendritic localization. The presence of PDL with LN or FN on the PLGA films was essential for increased neural cell growth. Also, PLGA films coated with either PDL/LN or PDL/FN mixtures had higher neurite outgrowth and regular differentiation.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherKluwer Academic Publishers-
dc.relation.isPartOfBIOTECHNOLOGY LETTERS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAnimals-
dc.subject.MESHCells, Cultured-
dc.subject.MESHFluorescent Antibody Technique-
dc.subject.MESHGlycolates/chemistry*-
dc.subject.MESHImmunohistochemistry-
dc.subject.MESHLactic Acid-
dc.subject.MESHMicroscopy, Electron, Scanning-
dc.subject.MESHNeurites*-
dc.subject.MESHNeurons/cytology*-
dc.subject.MESHNeurons/ultrastructure-
dc.subject.MESHPolyglycolic Acid-
dc.subject.MESHPolylactic Acid-Polyglycolic Acid Copolymer-
dc.subject.MESHRats-
dc.subject.MESHSurface Properties-
dc.titleEnhanced neurite outgrowth of rat neural cortical cells on surface-modified films of poly(lactic-co-glycolic acid)-
dc.typeArticle-
dc.publisher.locationNetherlands-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentYonsei Biomedical Research Center (연세의생명연구원)-
dc.contributor.departmentDept. of Medical Engineering (의학공학교실)-
dc.contributor.departmentDept. of Medical Engineering (의학공학교실)-
dc.contributor.googleauthorDong-Wook Han-
dc.contributor.googleauthorMin Sub Lee-
dc.contributor.googleauthorBong Joo Park-
dc.contributor.googleauthorJeong Koo Kim-
dc.contributor.googleauthorJong-Chul Park-
dc.identifier.doi10.1007/s10529-004-6585-2-
dc.contributor.localIdA01482-
dc.contributor.localIdA01662-
dc.contributor.localIdA04275-
dc.relation.journalcodeJ00336-
dc.identifier.eissn1573-6776-
dc.identifier.pmid15685420-
dc.identifier.urlhttp://link.springer.com/article/10.1007%2Fs10529-004-6585-2-
dc.subject.keywordextracellular matrix-
dc.subject.keywordneurite outgrowth-
dc.subject.keywordpoly(lactic-co-glycolic acid)-
dc.subject.keywordrat neural cortical cell-
dc.contributor.alternativeNamePark, Bong Joo-
dc.contributor.alternativeNamePark, Jong Chul-
dc.contributor.alternativeNameHan, Dong Wook-
dc.citation.volume27-
dc.citation.number1-
dc.citation.startPage53-
dc.citation.endPage58-
dc.identifier.bibliographicCitationBIOTECHNOLOGY LETTERS, Vol.27(1) : 53-58, 2005-
dc.date.modified2017-05-04-
dc.identifier.rimsid40234-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Medical Engineering (의학공학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
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