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음경 및 음낭에 발생한 유방외 파제씨병: 진단, 치료 및 예후

Other Titles
 Extramammary Paget's Disease of Penis and Scrotum: Diagnosis, Treatment and Prognosis 
Authors
 양원재  ;  김동석  ;  임영재  ;  조강수  ;  나군호  ;  조남훈  ;  최영득 
Citation
 KOREAN JOURNAL OF UROLOGY, Vol.46(2) : 159-162, 2005 
Journal Title
 KOREAN JOURNAL OF UROLOGY 
ISSN
 0494-4747 
Issue Date
2005
MeSH
Extramammary Paget's disease ; Penis ; Scrotum
Keywords
Extramammary Paget's disease ; Penis ; Scrotum
Abstract
Purpose: Penile and scrotal involvements in extramammary Paget's disease (EMPD) are exceedingly rare, with only small series or case reports having been reported in the literature. Our study was undertaken to clarify the uncertainty of the clinical outcome of this disease. Materials and Methods: Between 1995 and 2003, 32 patients with penile or scrotal EMPD were treated and followed up. Local wide excision was performed in all patients, with or without an intraoperative frozen biopsy. Results: Of the 32 patients, 12 (37.5%) underwent local wide excision with an intraoperative frozen biopsy; 1 patient (8.3%) had a positive surgical margin. Conversely, 20 (62.5%) underwent local wide excision with an excessive surgical margin of upto 1 to 2cm only due to the gross findings, but 15 (75.0%) had a positive surgical margin (p<0.001). 8 of the 16 patients with a positive surgical margin had a local recurrence at the 8 month follow-up (p<0.05). One patient with invasion to the subcutaneous tissue had died of metastatic EMPD and internal malignancy (renal cell carcinoma) at the 17 month postoperative follow-up. There was no underlying adnexal carcinoma in any case. Conclusions: Local wide excision with intraoperative frozen biopsy was essential for the complete treatment of EMPD. There was no associated internal malignancy or underlying adnexal carcinoma at the initial diagnoses.
Files in This Item:
T200500105.pdf Download
DOI
OAK-2005-02592
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
Yonsei Authors
Rha, Koon Ho(나군호) ORCID logo https://orcid.org/0000-0001-8588-7584
Cho, Kang Su(조강수) ORCID logo https://orcid.org/0000-0002-3500-8833
Choi, Young Deuk(최영득) ORCID logo https://orcid.org/0000-0002-8545-5797
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/147363
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