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진행성 간세포암종에서 동시 항암화학방사선 치료 후 발생한 급성 간기능 악화 2예

Other Titles
 Two Cases of Acute Hepatic Decompensation after Concurrent Chemoradiotherapy in Patients with Advanced Hepatocellular Carcinoma 
Authors
 김명환  ;  안상훈  ;  백용한  ;  이관식  ;  전재윤  ;  문영명  ;  성진실  ;  한광협 
Citation
 Journal of the Korean Liver Cancer Study Group (대한간암연구학회지), Vol.5(1) : 52-56, 2005 
Journal Title
 Journal of the Korean Liver Cancer Study Group (대한간암연구학회지) 
ISSN
 2233-6389 
Issue Date
2005
MeSH
Concurrent chemoradiotherapy ; Hepatitis B virus ; Lamivudine ; Hepatocellular carcinoma
Keywords
Concurrent chemoradiotherapy ; Hepatitis B virus ; Lamivudine ; Hepatocellular carcinoma
Abstract
Advanced hepatocellular carcinoma with portal vein thrombosis has a poor prognosis. Concurrent chemoradiation (CCRT) therapy achieved favorable results in advanced hepatocellular carcinoma with portal vein thrombosis and can be considered as a treatment option for the management of advanced hepatocellular carcinoma.2 But, exacerbation of liver function during concurrent chemoradiotherapy is a critical complication in patients with hepatitis B virus (HBV) related HCC. Reactivation of HBV replication is a well-known complication in cancer patients receiving chemotherapy. We report two cases with acute exacerbation of liver function. The one resulted in hepatic decompensation after CCRT probably due to HCC progression and/or chemoradiotherapy and the other is due to reactivation of HBV replication after CCRT, who recovered after lamivudine and corticosteroid therapy.
Full Text
http://kiss.kstudy.com/thesis/thesis-view.asp?key=2446212
Files in This Item:
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DOI
OAK-2005-02283
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
Yonsei Authors
Kim, Myoung Hwan(김명환)
Paik, Yong Han(백용한)
Seong, Jin Sil(성진실) ORCID logo https://orcid.org/0000-0003-1794-5951
Ahn, Sang Hoon(안상훈) ORCID logo https://orcid.org/0000-0002-3629-4624
Lee, Kwan Sik(이관식) ORCID logo https://orcid.org/0000-0002-3672-1198
Chon, Chae Yoon(전재윤)
Han, Kwang-Hyub(한광협) ORCID logo https://orcid.org/0000-0003-3960-6539
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/147264
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