84 198

Cited 7 times in

Usefulness of Measuring Serum Procalcitonin Levels in Patients with Inflammatory Bowel Disease.

Authors
 Sook Hee Chung  ;  Hye Won Lee  ;  Seung Won Kim  ;  Soo Jung Park  ;  Sung Pil Hong  ;  Tae Il Kim  ;  Won Ho Kim  ;  Jae Hee Cheon 
Citation
 Gut and Liver, Vol.10(4) : 574-580, 2016 
Journal Title
 Gut and Liver 
ISSN
 1976-2283 
Issue Date
2016
MeSH
Adult ; Behcet Syndrome/blood* ; Behcet Syndrome/microbiology ; Biomarkers/blood ; C-Reactive Protein/analysis ; Calcitonin/blood* ; Female ; Humans ; Inflammatory Bowel Diseases/blood* ; Inflammatory Bowel Diseases/microbiology ; Male ; Middle Aged ; Predictive Value of Tests ; Retrospective Studies ; Sepsis/blood ; Sepsis/diagnosis* ; Sepsis/microbiology ; Severity of Illness Index ; Young Adult
Keywords
Disease activity ; Infection ; Inflammatory bowel disease ; Intestinal Behçet’s disease ; Procalcitonin
Abstract
BACKGROUND/AIMS: The relationships between serum procalcitonin, inflammatory bowel disease (IBD) and intestinal Behçet's disease (BD) have not been completely determined. We aimed to evaluate the usefulness of measuring serum procalcitonin levels to assess disease activity and infection stage in patients with IBD and intestinal BD. METHODS: We retrospectively analyzed clinical data from 129 patients with IBD and intestinal BD for whom serum procalcitonin and C-reactive protein (CRP) levels were measured between January 2006 and February 2013. RESULTS: The median serum procalcitonin levels in the IBD and intestinal BD with septic shock or sepsis (n=8), with localized infection (n=76), and without infection (n=45) were 3.46 ng/mL (range, 0.17 to 63.66 ng/mL), 0.22 ng/mL (range, 0.05 to 140.18 ng/mL), and 0.07 ng/mL (range, 0.00 to 31.50 ng/mL), respectively (p=0.001). The serum CRP levels in the IBD and intestinal BD patients did not differ according to the infection stage. Variations in serum procalcitonin levels were not observed in the IBD and intestinal BD patients with different disease activities. CONCLUSIONS: Serum procalcitonin levels may not be affected by IBD and intestinal BD activity itself, although they may be affected by concomitant infection. Serum procalcitonin measurements could be more useful than CRP in determining the infection stage that reflects the severity of infection in IBD and intestinal BD patients.
Files in This Item:
T201602595.pdf Download
DOI
10.5009/gnl15209
Appears in Collections:
1. College of Medicine (의과대학) > BioMedical Science Institute (의생명과학부) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Seung Won(김승원) ORCID logo https://orcid.org/0000-0002-1692-1192
Kim, Won Ho(김원호) ORCID logo https://orcid.org/0000-0002-5682-9972
Kim, Tae Il(김태일) ORCID logo https://orcid.org/0000-0003-4807-890X
Park, Soo Jung(박수정)
Lee, Hye Won(이혜원) ORCID logo https://orcid.org/0000-0002-3552-3560
Cheon, Jae Hee(천재희) ORCID logo https://orcid.org/0000-0002-2282-8904
Hong, Sung Pil(홍성필)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/147211
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse