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Difference in Bone Mineral Density Change at the Lateral Femoral Cortices according to Administration of Different Bisphosphonate Agents.

DC FieldValueLanguage
dc.contributor.author김성준-
dc.contributor.author양규현-
dc.contributor.author정우석-
dc.date.accessioned2017-02-27T08:06:06Z-
dc.date.available2017-02-27T08:06:06Z-
dc.date.issued2016-
dc.identifier.issn2287-6375-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/147081-
dc.description.abstractBACKGROUND: To retrospectively assess whether the response of subtrochanteric lateral cortex (STLC) is different according to the bisphosphonate agents in terms of bone mineral density (BMD) change. METHODS: A total of 149 subjects, who had 2- to 4-year interval follow-up of BMD using dual energy X-ray absorptiometry (DXA), were included in this retrospective study divided into following 3 groups: control group (no consumption of any anti-osteoporotic drugs, n=38), alendronate group (naïve alendronate users, n=48), risedronate group (naïve risedronate users, n=63). BMD was measured at the STLC and subtrochanteric medial cortex (STMC) in each patient by drawing rectangular ROIs at the bone cortices. The percent change of BMD at the STLC were compared between the aforementioned 3 groups by using analysis of covariance model to control five independent variables of age, body mass index, percent change of STMC, hip axis length, time interval between DXA examinations. RESULTS: The least square mean values±standard deviation of the percent change of BMD in the control, alendronate, and risedronate groups were 1.46±1.50, 2.23±1.26, and 6.96±1.11, respectively. The risedronate group showed significantly higher change of BMD percentage compared with the control (adjusted P=0.012) or alendronate (adjusted P=0.016) groups. CONCLUSIONS: The percent change of BMD at the STLC in the risedronate user group was greater than the alendronate and control groups. The implication of these changes needs to be further verified.-
dc.description.statementOfResponsibilityopen-
dc.format.extent85~93-
dc.languageEnglish-
dc.publisherKorean Society for Bone and Mineral Research-
dc.relation.isPartOfJournal of Bone Metabolism-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleDifference in Bone Mineral Density Change at the Lateral Femoral Cortices according to Administration of Different Bisphosphonate Agents.-
dc.typeArticle-
dc.publisher.locationKorea (South)-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Radiology-
dc.contributor.googleauthorSungjun Kim-
dc.contributor.googleauthorHyun Hee Bang-
dc.contributor.googleauthorHanna Yoo-
dc.contributor.googleauthorIl Hyung Park-
dc.contributor.googleauthorKyu Hyun Yang-
dc.contributor.googleauthorHyunsun Lim-
dc.contributor.googleauthorWoo Seok Jung-
dc.identifier.doi10.11005/jbm.2016.23.2.85-
dc.contributor.localIdA00585-
dc.contributor.localIdA02282-
dc.contributor.localIdA04669-
dc.relation.journalcodeJ02875-
dc.relation.journalsince2012~-
dc.identifier.pmid27294080-
dc.relation.journalbefore~2011 JBM : Journal of Bone Metabolism-
dc.subject.keywordAlendronate-
dc.subject.keywordBone density-
dc.subject.keywordFemur-
dc.subject.keywordRisedronate-
dc.contributor.alternativeNameKim, Sung Jun-
dc.contributor.alternativeNameYang, Kyu Hyun-
dc.contributor.alternativeNameJung, Woo Seok-
dc.contributor.affiliatedAuthorKim, Sung Jun-
dc.contributor.affiliatedAuthorYang, Kyu Hyun-
dc.contributor.affiliatedAuthorJung, Woo Seok-
dc.citation.volume23-
dc.citation.number2-
dc.citation.startPage85-
dc.citation.endPage93-
dc.identifier.bibliographicCitationJournal of Bone Metabolism, Vol.23(2) : 85-93, 2016-
dc.date.modified2017-02-24-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실) > 1. Journal Papers

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