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Relationship between non-alcoholic fatty liver disease, metabolic syndrome and insulin resistance in Korean adults: A cross-sectional study

DC Field Value Language
dc.contributor.author이지원-
dc.contributor.author이향규-
dc.contributor.author추상희-
dc.date.accessioned2017-02-24T11:46:40Z-
dc.date.available2017-02-24T11:46:40Z-
dc.date.issued2016-
dc.identifier.issn0009-8981-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/146859-
dc.description.abstractBACKGROUND: We investigated the independent and combined impact of obesity and nonalcoholic fatty liver disease (NAFLD) on components and prevalence of metabolic syndrome in Korean adults. METHODS: This study included 1695 adults (500 males and 1,195 females), who took part in a regular health check-up at the community-based health promotion center. Participants were divided according to degree of adiposity and the presence of NAFLD. The components and prevalence of metabolic syndrome were compared. RESULTS: Fasting glucose was significantly higher in nonobese participants with NAFLD compared to obese participants without NAFLD. Logistic regression analysis revealed that the presence of NAFLD was associated with 3.63 times increased prevalence of metabolic syndrome (95% CI: 1.21-10.86) while obesity without NAFLD was associated with 3.84 times increased prevalence of metabolic syndrome (95% CI: 1.57-9.36) in male. In female, the presence of NAFLD was associated with 5.56 times higher prevalence of metabolic syndrome (95% CI: 2.53-12.23) while obesity without NAFLD had 3.46 times increased prevalence of metabolic syndrome (95% CI: 1.64-7.33). CONCLUSIONS: NAFLD is associated with the prevalence of metabolic syndrome, independent of adiposity. In females, NAFLD may be a more important factor than obesity for risk of metabolic syndrome.-
dc.description.statementOfResponsibilityrestriction-
dc.format.extent12~17-
dc.languageEnglish-
dc.publisherElsevier-
dc.relation.isPartOfCLINICA CHIMICA ACTA-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdiposity-
dc.subject.MESHBlood Glucose/analysis-
dc.subject.MESHCross-Sectional Studies-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHInsulin Resistance*-
dc.subject.MESHMale-
dc.subject.MESHMetabolic Syndrome/blood*-
dc.subject.MESHMetabolic Syndrome/epidemiology-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNon-alcoholic Fatty Liver Disease/blood*-
dc.subject.MESHNon-alcoholic Fatty Liver Disease/epidemiology-
dc.subject.MESHObesity/blood-
dc.subject.MESHObesity/epidemiology-
dc.subject.MESHPrevalence-
dc.subject.MESHRepublic of Korea-
dc.titleRelationship between non-alcoholic fatty liver disease, metabolic syndrome and insulin resistance in Korean adults: A cross-sectional study-
dc.typeArticle-
dc.publisher.locationNetherlands-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Family Medicine-
dc.contributor.googleauthorJi Young Kim-
dc.contributor.googleauthorChoae Lee-
dc.contributor.googleauthorMinsuk Oh-
dc.contributor.googleauthorJee-Aee Im-
dc.contributor.googleauthorJi-Won Lee-
dc.contributor.googleauthorSang Hui Chu-
dc.contributor.googleauthorHyangkyu Lee-
dc.contributor.googleauthorJustin Y. Jeon-
dc.identifier.doi10.1016/j.cca.2016.03.018-
dc.contributor.localIdA03203-
dc.contributor.localIdA03282-
dc.contributor.localIdA04232-
dc.relation.journalcodeJ00543-
dc.identifier.eissn1873-3492-
dc.identifier.pmid27020118-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0009898116301036-
dc.subject.keywordInsulin resistance-
dc.subject.keywordMetabolic syndrome-
dc.subject.keywordNon-alcoholic fatty liver disease-
dc.contributor.alternativeNameLee, Ji Won-
dc.contributor.alternativeNameLee, Hyang Kyu-
dc.contributor.alternativeNameChoo, Sang Hee-
dc.contributor.affiliatedAuthorLee, Ji Won-
dc.contributor.affiliatedAuthorLee, Hyang Kyu-
dc.contributor.affiliatedAuthorChoo, Sang Hee-
dc.citation.volume458-
dc.citation.startPage12-
dc.citation.endPage17-
dc.identifier.bibliographicCitationCLINICA CHIMICA ACTA, Vol.458 : 12-17, 2016-
dc.date.modified2017-02-24-
dc.identifier.rimsid47954-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실) > 1. Journal Papers
3. College of Nursing (간호대학) > Dept. of Nursing (간호학과) > 1. Journal Papers

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